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Arienti, Silvia (2008) Studio prospettico su pazienti affette da connettivite indifferenziata in gravidanza;confronto con Lupus Eritematoso e Sindrome di Sjogren. [Tesi di dottorato]

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Abstract (inglese)

Undifferentiated connective tissue disease (UCTD) is a term used to identify a group of patient that while presenting common symptoms of systemic connective disease does not fulfil the criteria for a definite connective tissues disease. Arthralgias, Raynaud, mild fever and anti nuclear antibodies common features in UCTD patients.
We have prospectively followed 50 pregnancies in 43 women with UCTD, 142 pregnancies in 111 women with SLE and 35 pregnancies in 26 women with primary Sjögren’s Syndrome.
In UCTD women the mean gestational age at delivery was 38.6 weeks, the prevalence of pregnancy loss 2%, preterm birth 2%, cesarean sections 30.5%, Premature Rupture of Membrane (PROM) 0%, preeclampsia 0%, Intra Uterine Growth Retardation (IUGR) 8.2% and newborns Small for Gestational Age (SGA) 12.2%; average weight at birth was 3062.5 g.
In SLE group the mean gestational age at delivery was 37.8 weeks, prevalence of pregnancy loss 14.7% (p < 0.005 vs UCTD), preterm birth 22.5%, cesarean sections 61.7%, PROM 8%, preeclampsia 4.2%, IUGR 1.7% and SGA 12.1%; average weight at birth was 2876.8 g (p < 0.05 vs UCTD).
In women with Sjögren syndrome the mean gestational age at delivery was 38.5 weeks, prevalence of pregnancy loss 8.6%, preterm birth 13.9%, cesarean sections 29.4%, PROM 3.1%, preeclampsia 0%, IUGR 3.1% and SGA 6.3%.
Conclusion: the general outcome of UCTD pregnancies is similar to that observed in women with primary Sjögren’s syndrome, and better than in SLE women. No patients evolved into a definite CTD, nor required an important modification of therapy during and after pregnancy. The general outcome of these pregnancies is now excellent, if prospectively followed by multidisciplinary teams with great experience in this field.


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Tipo di EPrint:Tesi di dottorato
Relatore:Doria, Andrea
Dottorato (corsi e scuole):Ciclo 20 > Scuole per il 20simo ciclo > SCIENZE MEDICHE, CLINICHE E SPERIMENTALI > REUMATOLOGIA CLINICA E SPERIMENTALE
Data di deposito della tesi:2008
Anno di Pubblicazione:2008
Parole chiave (italiano / inglese):CONNETTIVITE INDIFFERENZIATA, GRAVIDANZA, SJOGREN, LUPUS ERITEMATOSO SISTEMICO.
Settori scientifico-disciplinari MIUR:Area 06 - Scienze mediche > MED/16 Reumatologia
Struttura di riferimento:Dipartimenti > Dipartimento di Medicina Clinica e Sperimentale
Codice ID:1014
Depositato il:09 Ott 2008
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Le url contenute in alcuni riferimenti sono raggiungibili cliccando sul link alla fine della citazione (Vai!) e tramite Google (Ricerca con Google). Il risultato dipende dalla formattazione della citazione.

1. Davidson A, Diamond B. Autoimmune disorders. N Engl J Med 2001; 345: 340-50. Cerca con Google

2. Doria A, Mosca M, Gambari PF, Bombardieri S. Defining unclassifiable connective tissue diseases: incomplete, undifferentiated, or both? J Rheumatol 2005; 32: 213-5. Cerca con Google

3. Mosca M, Neri R, Bencivelli W, et al. Undifferentiated connective tissue disease: analysis of 83 patients with a minimum follow-up of 5 years. J Rheumatol 2002; 29: 2345-9. Cerca con Google

4. Alarcòn GS, Williams GV, Singer JZ, Steen VD, Clegg DO, Paulus HE, et al. Early undifferentiated connective tissue disease. I Early clinical manifestations in a large cohort of patients with undifferentiated connective tissue diseases compared with cohorts of well established connective tissue diseases. J Rheumatol 1991: 18: 1332-9. Cerca con Google

5. Alarcòn GS, Willkens RF, Ward JR, Clegg DO, Morgan JG, Ma K, et al. Early undifferentiated connective tissue disease. IV. Musculoskeletal manifestations in a large cohort of patients with undifferentiated connective tissue diseases compared with cohorts of patients with well-established connective tissue diseases: follow up analyses in patients with unexplained polyarthritis and patients with rheumatoid arthritis at baseline. Arthritis Rheum 1996; 39: 403-14. Cerca con Google

6. Om-Orta H, Alarcon-Segovia D, Diaz-Jouanen E. Systemic lupus erythematosus: differences between patients who do and do not fulfill classification criteria at the time of diagnosis. J Rheumatol 1980; 7: 831-37. Cerca con Google

7. Calvo-Alén J, Alarcòn GS, Burgard SL, Burst N, Bartolucci AA, Williams HJ. Systemic lupus erythematosus: Predictors of its occurrence among a cohort of patients with early undifferentiated connective disease: multivariate analyses and identification of risk factors. J Rheumatol 1996; 23: 469-75. Cerca con Google

8. Williams HJ, Alarcòn GS, Joks R, Steen VD, Bulpitt K, Clegg DO. Early undifferentiated tissue disease. V. An inception cohort after 10 years: disease remission and changes in diagnoses in well established and undifferentiated CTD. J Rheumatol 1999; 26: 816-25. Cerca con Google

9. Mosca M, Tavoni A, Neri R, Bencivelli W, Bombardieri S. Undifferentiated connective tissue diseases: the clinical and sierological profiles in 91 patients followed for at least 1 year. Lupus 1998; 7: 95-100. Cerca con Google

10. Danieli MG, Fraticelli P, Salvi A, Gabrielli A, Danieli G. Undifferentiated connective tissue disease: Natural history and evolution into definite CTD assessed in 84 patients initially diagnosed as early UCTD. Clin Rheumatol 1998; 17: 195-201. Cerca con Google

11. Danieli MG, Fraticelli P, Franceschini F, Cattaneo R, Farsi A, Passaleva A. Five-year follow up of 165 Italian patients with undifferentiated connective tissue diseases. Clin Exp Rheumatol 1999; 17: 585-91. Cerca con Google

12. Dijkstra S, Nieuwenhuys EJ, Swaak AJ. The prognosis and outcome of patients referred to an outpatient clinic for rheumatic diseases characterized by the presence of antinuclear antibodies (ANA). Scand Rheumatol 1999; 28: 33-7. Cerca con Google

13. Williams HJ, Alarcòn GS, Neuner R, Steen VD, Bulpitt K, Clegg DO, et al. Early undifferentiated tissue disease.V. An inception cohort 5 years later: disease remission and changes in diagnoses in well established and undifferentiated connective tissue diseases. J Rheumatol 1998; 25: 261-8. Cerca con Google

14. Clegg DO, Williams HJ, Singer JZ, Steen VD, Schlegel S, Ziminski C, et al. Early undifferentiated connective tissue disease. II. The frequency of circulating antinuclear antibodies in patients with early rheumatic diseases. J Rheumatol 1991; 18: 1340-3. Cerca con Google

15. Mosca M, Neri R, Bombardieri S. Undifferentiated connective tissue diseases (UCTD): a review of the literature and a proposal for preliminary classification criteria. Clin Exp Rheumatol 1999; 17: 615-20. Cerca con Google

16. Cavazzana I, Franceschini F, Belfiore M, Quinzanini M, Caporali R, Calzavara- Pinton P, et al. Undifferentiated connective tissue disease with antibodies to Ro/SSA: clinical features and follow-up of 148 patients. Clin Exp Rheumatol 2001; 19: 403-9. Cerca con Google

17. Mosca M, Tani C, Bombardieri S. Undifferentiatedbconnective tissue diseases (UCTD): a new frtontier for rheumatology. Best Practice & Research Clinical Rheumatology 2007; 21 (6): 1011-23. Cerca con Google

18. Mosca M, Tani C, Neri C, Baldini C, Bombardieri S. Undifferentiated connective tissue diseases (UCTD). Autoimmunity Reviews 2006; 6: 1-4. Cerca con Google

19. Mosca M, Baldini C, Bombardieri S. Undifferentiated connective tissue diseases in 2004. Clin Exp Rheumatol. 2004; 22 (3 Suppl 33): S14-8. Cerca con Google

20. Fries JF, Hochberg MC, Medsger TA, Hunder GG, Bombardier C, and the American College of Rheumatology Diagnostic and Therapeutic Criteria Committee. Criteria for rheumatic disease. Different types and different functions. Arthritis Rheum 1994; 4: 454-62. Cerca con Google

21. Doria A, Vesco P, Zulian F, Gambari PF. The 1982 ARA/ACR criteria for classification of systemic lupus erythematosus in pediatric age. Clin Exp Rheumatol 1994; 12: 689-90. Cerca con Google

22. Doria A, Ghirardello A, de Zambiasi P, Ruffatti A, Gambari P.F. Japanese diagnostic criteria for mixed connective tissue disease in Caucasian patients. J Rheumatol 1992; 19: 259-64. Cerca con Google

23. Smith EL, Shmerling RH. The American College of Rheumatology criteria for the classification of systemic lupus erythematosus: strengths, weaknesses, and opportunity for improvement. Lupus 1999; 8: 586-95. Cerca con Google

24. Ganczarczyk L, Urowitz MB, Gladman DD. “Latent lupus” J Rheumatol 1989; 16: 475-8. Cerca con Google

25. Members of the study group of incomplete SLE and SLE with disease duration longer than 10 years. Incomplete lupus erythematosus: result of a multicenter study under the supervision of the EULAR Standing Committee on International Clinical Studies including therapeutic trials (ESCISIT). Rheumatology 2001; 40: 89-94. Cerca con Google

26. Bodolay E, Csiki Z, Szekanecz Z, Ben T, Kiss E, Zeher M, Szücs, Dankò K, Szegedi G. Five-year follow-up of 665 Hungarian patients with undifferentiated connective tissue disease (UCTD). Clin Exp Rheumatol 2003; 21: 313-20. Cerca con Google

27. Venables PJ. Undifferentiated connective tissue diseases: mixed or muddled? Lupus 1998; 7: 73-4. Cerca con Google

28. Arbuckle MR, McClain MT, Rubertone MV, Scofield RH, Dennis GJ, James JA, et al. Development of autoantibodies before the clinical onset of systemic lupus erythematosus. N Engl J Med 2003; 349: 1526-33. Cerca con Google

29. Tan EM, Cohen AS, Fries JF, Masi AT, McShane DJ and Rothfield NF et al. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1982; 25: 1271-7. Cerca con Google

30. Hocheberg MC. Updating the American College of Rheumatology revised crteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1997; 40: 1725. Cerca con Google

31. Zampieri S., Ghirardello A., Doria A., Tonello M., Bendo R., Rossini K., Gambari P.F. The use of Tween 20 in immunoblotting assays for the detection of autoantibodies in connective tissue diseases. J Immunol Methods 239: 1-11, 2000. Cerca con Google

32. Villata D, Romelli PB, Savina C, Bizzarro N, Bozzoli R, Tonutti E, Ghirardello A, Doria A. Anti-dsDNA antibody avidity determination by simple reliable ELISA method for SLE diagnosis and monitoring. Lupus 2003; 12: 31-6. Cerca con Google

33. Ghirardello A, Doria A, Zampieri S, Gerli R, Rapizzi E, Gambari PF. Anti-ribosomal P protein antibodies detected by immunoblotting in patients with connective tissue diseases: their specificity for SLE and the association with the IgG anticardiolipin antibodies. Ann Rheum Dis 2000; 59: 975-81. Cerca con Google

34. Ghirardello A, Caponi L, Franceschini F, Zampieri S, Gambari PF, Doria A. Diagnostic tests for antiribosomal P protein antibodies: a comparative evaluation of immunoblotting and ELISA assays. J Autoimmunity 2002; 19: 71-7. Cerca con Google

35. Chaouat G, Kolb J, Wegmann TG. The murine placenta as an immunological barrier between the mother and the fetus. Immunol Rev 1983; 75: 31-57. Cerca con Google

36. Sargent IL. Maternal and fetal immune responses during pregnancy. Exp Clin Immunogenet 1993; 10: 85-97. Cerca con Google

37. Falkoff R. Maternal immune function during pregnancy. In: Schatz M, Zeiger RS, Claman NH, editors. Asthma and immunological diseases in pregnancy and early infancy. New York: Marcel Dekker, 1998. p 73-99. Cerca con Google

38. First MR, Combs A, Weiskittel P, Miodovnik M. Lack of effect of pregnancy on renal allograft survival or function. Transplantation 1995; 59: 472-6. Cerca con Google

39. Carosella ED, Paul P, Moreau P, Rouas-Freiss N. HLA-G and HLA-E: fundamental and pathophysiological aspects. Immunol Today 2000; 21: 532-3. Cerca con Google

40. Münz C, Holmes N, King A, Loke YW, Colonna M, Schild H, Rammensee HG. Human Histocompatibility leukocyte antigen (HLA)-G molecules inhibit NKAT3 expressing natural killer cls. J Exp Med 1997; 185: 385-91. Cerca con Google

41. King A, Hiby SE, Verma S, Burrows T, Gardner L, Loke YW. Uterine NK cells and trophoblast HLA class I molecules. Am J Reprod Immunol 1997; 37: 459-62. Cerca con Google

42. Rukavina D, Podack ER, Rubesa G, Spanjol-Pandelo S, Randic L. Down-regulated expression of perforin-positive/CD16+ cells in the peripheral blood lymphocytes in the first trimester of pregnancy and up-regulation at the end of pregnancy. Am J Reprod Immunol 1997; 38: 189-96. Cerca con Google

43. Ljunggren HG, Kärre K. In search of the “missing self”: MHC molecules and NK cell recognition. Immunol Today 1990; 11: 237-44. Cerca con Google

44. Kaufmann S. ?? and other unconventional T lymphocytes: what do they see and what do they do? Proc Natl Acad Sci USA 1996; 93: 2272-79. Cerca con Google

45. Barakonyi A, Polgar B, Szekeres-Bartho J. The role of ?/?- cell receptor-positive cells in pregnancy: Part II. Am J Repr Immunol 1999; 42: 83-87. Cerca con Google

46. Raghupathy R. Th-1type immunity is incompatible with successful pregnancy. Immunol Today 1997; 18: 478-82. Cerca con Google

47. Margni RA e Malan Borel I. Role of asymmetric IgG antibodies in fetal maintenance. Curr Trends Immunol 1999; 2: 153-163. Cerca con Google

48. Da Silva JAP, Hall GM. The effects of gender and sex hormones on outcome in rheumatoid arthritis. Bailliere’s Clin Rheumatol 1992; 6: 193-219. Cerca con Google

49. Shuurs AHWM, Verheuel HAM. Effect of gender and sex steroids on the immune response. J Steroid Biochem 1990; 35: 157-72. Cerca con Google

50. Sthoeger ZN, Chiorazzi RG, Lahita RG. Regulation of the immune response by sex steroids. J Immunol 1988; 141: 91-8. Cerca con Google

51. Grossman CJ. Interaction between the gonadal steroids and the immune system. Science 1985; 227: 257-61. Cerca con Google

52. McMurray RW, May W. Sex hormones and systemic lupus erythematosus. Arthritis Rheum 2003; 48; 8: 2100-10. Cerca con Google

53. Petri M, Robinson C. Oral contraceptive and systemic lupus. Arthritis Rheum 1997; 40; 797-803. Cerca con Google

54. Yang LY, Huang WJ, Chen WP, Fu LW, Lin CY. Does parental oestrogen therapy flare up disease activity in patient with systemic lupus erythematosus complicated by haemorragic cystitis? Rheumatology (Oxford) 1999; 38: 372-3. Cerca con Google

55. Ben-Chetrit A, Ben-Chetrit E. Systemic lupus erythematosus induced by ovulation induction treatment. Arthritis Rheum 1994; 37: 1614-7. Cerca con Google

56. Casoli P, Tumiati B, La Sala G. Fatal exacerbation of SLE after induction of ovulation. J Rheumatol 1997; 24: 1639-40. Cerca con Google

57. Mok CC, Wong RW, Lau CS. Ovarian failure and flares of systemic lupus erythematosus. Arthritis Rheum 1999; 42: 1274-80. Cerca con Google

58. Branch DW. Physiologic Adaptation of pregnancy. Am J Reprod Immunol 1992; 28: 120-12. Cerca con Google

59. Wegmann TG, Lin H, Guilbert L, Mosmann TR. Bidirectional cytokine interactions in the maternal-fetal relationship: is successful pregnancy a Th2 phenomenon? Immunol Today 1993; 14: 353-6. Cerca con Google

60. Marzi M, Vigano A, Trabattoni D, Vira ML, Salvalaggio A, Clerici E, Clerici M. Characterization of type 1 and type 2 cytokine production profile in physioogic and pathologic human pregnancy. Clin Exp Immunol 1996; 106: 127-33. Cerca con Google

61. Piccinni MP, Guidizi MG, Biagiotti R, Beloni L, Giannarini L, Sampognaro S, Parronchi P, Manetti R, Annunziato F, Livi C, Romagnani S, Maggi E. Progesterone favors the development of human T helper cell producing Th-2 type cytokines and promotes both IL-4 production and membrane CD expression in established Th1 cell clones. J Immunol 1995; 155: 128-33. Cerca con Google

62. Saito S, Harada N, Ishii N, Morii T, Sakakura S, Enomoto M, Umekage H, Nishikawa K, Marita N, Nakamura M,Sugamura K, Morikawa H. Functional expression on human trophoblasts of interleukin 4 and interleukin 7 receptor complexes with common ? chain. Biochem Res Commum 1997; 231: 429- 34. Cerca con Google

63. Opsjøn SL, Wether NC, Tinglstad S, Wiedswang G, Sunden A, Waager A, Austejuler R. Tumor necrosis factor, interleukin-1, and interleukin-6 in normal human pregnancy. Am J Obstet Gynecol 1993; 169: 397-404. Cerca con Google

64. Szekeres-Bartho J, Wegmann TG. A progesterone-dependent immunomodulatory protein alters the Th1/Th2 balance. J Reprod Immunol 1996; 31: 81-95. Cerca con Google

65. Piccinni MP, Scaletti C, Maggi E, Romagnani S. Role of hormone-controlled Th1- and Th2-type cytokines in successful pregnancy. J Neuroimmunol 2000; 109: 30-3. Cerca con Google

66. Elenkov IJ, Hoffmann J, Wilder RL. Does differential neuroendocrine control of cytokine production govern the expression of autoimmune diseases in pregnancy and the postpartum period? Mol Med Today 1997; 3: 379-83. Cerca con Google

67. Ramirez F, Fowell DJ, Puklavec M, Simmonds S. Mason D. Glucocorticoids promote a Th2 cytokine response by CD4+ T cells in vitro. J Immunol 1996; 156: 2406-12. Cerca con Google

68. Lahita RG. The role of sex hormones in systemic lupus erythematosus. Curr Opin Rheum 1999; 11: 352-56. Cerca con Google

69. Tincani A, Biasini Rebaioli C, Frassi M, Taglietti M, Gorla R, Cavazzana I, Faden D, Taddei F, Lojacono A, Motta M, Trepidi L, Meroni P, Cimaz R, Ghirardello A, Doria A, Pisoni MP, Muscarà M, Brucato A. Pregnancy and autoimmunity: maternal treatment and maternal disease influence on pregnancy outcome. Autoimmunity Rev 2005; 4: 423-428. Cerca con Google

70. Doria A, Iaccarino L, Ghirardello A, Briani C, Zampieri S, Tarricone E, Gambari PF. Pregnancy in rare autoimmune rheumatic diseases: UCTD, MCTD, myositis, systemic vasculitis and Beçhet disease. Lupus. 2004; 13 (9): 690-5. Cerca con Google

71. Fraga A, Mintz G, Orozco J, Orozco JH: Sterility and fertility rates, fetal wastage and maternal morbidity in systemic lupus erythematosus. J Rheumatol 1974; 1: 293-8. Cerca con Google

72. Nossent HC, Swaak TJG: Systemic lupus erythematosus. VI. Analysis of the interrelationship with pregnancy. J Rheumatol 1990; 17: 771-6. Cerca con Google

73. Friedman EA, Rutherford JW: Pregnancy and lupus erythematosus. Obstet Gynecol 1956; 8: 601-10. Cerca con Google

74. Lockshin MD, Reinitz E, Druzin ML, Murrman M, Estes D. Lupus pregnancy: Casecontrol prospective study demonstrating absence of lupus exacerbation during or after pregnancy. Am J Med 1984; 77: 893-8. Cerca con Google

75. Mintz G, Nitz J, Gutierrez G, Garcia-Alonso A, Karchmer S. Prospective study of pregnancy in systemic lupus erythematosus: results of a multi-disciplinary approach. J Rheumatol 1986; 13: 732-9. Cerca con Google

76. Urowitz MB, Gladman DD, Farewell VT, Stewart J, McDonald J. Lupus and pregnancy studies. Arthritis Rheum 1993; 36 : 1392-7. Cerca con Google

77. Wong KL, Chan FY, Lee XP. Outcome of pregnancy in patients with systemic lupus erythematosus. A prospective study. Arch Intern Med 1991; 151: 269-73. Cerca con Google

78. Petri M, Howard D, Repke J. Frequency of lupus flare in pregnancy: the Hopkins lupus pregnancy center experience. Arthritis Rheum 1991; 34: 1538-45. Cerca con Google

79. Ruitz-Irastorza G, Lima F, Alves J, Khamashta MA, Simpson J, Hughes GRV, Buchanan NMM. Increased rate of lupus flare during pregnancy and the puerperium. Br J Rheumatol 1996; 35: 133-8. Cerca con Google

80. Gimovsky ML, Montoro M. Systemic Lupus Erythematosus and other connective tissue diseases in pregnancy. Clin Obstet Gynecol 1991; 34: 35-50. Cerca con Google

81. Lockshin MD. Lupus pregnancy. Clin Rheum Dis 1985; 11: 611-32. Cerca con Google

82. Khamashta MA, Hughes GRV. Pregnancy in systemic lupus erythematosus. Curr Opin Rheumatol 1996; 8: 424-9. Cerca con Google

83. Boumpas DT, Balow JE. Outcome criteria for lupus nephritis trials: a critical overview. Lupus 1998; 7: 622-9. Cerca con Google

84. Garsenstein M, Pollak VE, Kark RM. Systemic lupus erythematosus and pregnancy. New Engl J Med 1962; 267: 165-9. Cerca con Google

85. Packham DK, Lam SS, Nicholls K, Fairley KF, Kincaid-Smith PS. Lupus nephritis and pregnancy. Q J Med 1992; 83: 315-24. Cerca con Google

86. Julkunen H, Kaaja R, Palosuo T, Gronhager-Riska C, Teramo K. Pregnancy in lupus nephropaty. Acta Obstet Gynecol Scand 1993; 72: 258-63. Cerca con Google

87. Buyon JP, Cronstein BN, Morris M., Tanner M, Weissmann G. Serum complement values (C3 and C4) to differentiate between systemic lupus activity and pre-eclampsia. Am J Med 1986; 21: 194-200. Cerca con Google

88. Kitridou RC. The mother in systemic lupus erythematosus. In : Wallace DJ, Hahn BH, eds. Dubois’ lupus erythematosus. 5th Ed. Baltimore: Williams & Wilkins, 1997: 967-1002. Cerca con Google

89. Petri M. Pregnancy in SLE. Ballieres Clin Rheumatol 1998; 12: 449-76. Cerca con Google

90. Nossent HC, Swaak TJ. Systemic lupus erythematosus. VI. Analysis of the interrelationship with pregnancy. J Rheumatol 1990; 17: 771-6. Cerca con Google

91. Martinez-Rueda JO, Arce-Salinas CA, Kraus A, Alcocer-Varela J, Alarcar-Segovia D. Factors associated with fetal losses in severe systemic lupus erythematosus. Lupus 1996; 5: 113-19. Cerca con Google

92. Rahman P, Gladman DD, Urowitz MB. Clinical predictors of fetal outcome in systemic lupus erythematosus. J Rheumatol 1998; 25: 1526-30. Cerca con Google

93. Ginsberg JS, Brill-Edwards P, Johnston M, Denburg JA, Andrew M, Burrows RF, Bensen W, Cividino A; Long AA. Relationship of antiphospholipid antibodies to pregnancy loss in patients with systemic lupus erythematosus: a cross-sectional study. Blood 1992; 80: 975-80. Cerca con Google

94. Petri M, Allbritton J. Fetal outcome of lupus pregnancy: a retrospective case-control study of the Hopkins Lupus Cohort. J Rheumatol 1993; 20: 650-6. Cerca con Google

95. Buyon JP, Yaron M, Lockshin MD. First international conference on rheumatic disease in pregnancy. Arthritis Rheum 1993; 36: 59-64. Cerca con Google

96. Petri M, Howard D, Repke J, Goldman DW. The Hopkins Lupus Pregnancy Center: 1987-1991 update. Am J Reprod Immunol 1992; 28: 188-91. Cerca con Google

97,. Cervera R, Piette JC, Font J, Khamashta MA, Shoenfeld Y, Camps MT, Jacobsen S, Lakos G, Tincani A, Kontopoulou-Griva I, Galeazzi M, Meroni PL, Derksen RH, de Groot PG, Gromnica-Ihile E, Baleva M, Mosca M, Bombardieri S, Houssiau F, Gris JC, Quere I, Hachulla E, Vasconcelos C, Roch B, Fernandez-Nebro A, Boffa MC, Hughes GR, Ingelmo M, Euro-Phospholipid Project Group. .Antiphospholipid syndrome: clinical and immunologic manifestations and patterns of disease expression in a cohort of 1000 patients. Arthritis Rheum 2002; 46: 1019-27 267). Cerca con Google

98. Tincani A, Faden D, Tarantini M, Lojacano A, Tarzi P, Gastaldi A, Dimario C, Spatola L, Caltano R, Balestrieri G. Systemic lupus erythematosus and pregnancy : a prospective study. Clin Exp Rheumatol 1992; 10: 439-46. Cerca con Google

99. Derksen RHWM, Bruinse HW, Groot PG, Kater L. Pregnancy in systemic lupus erythematosus: a prospective study. Lupus 1994; 3: 149-55 Cerca con Google

100. Takaya M, Ichikawa Y, Shimizu H, Uchiyama M, Moriuchi J, Arimori S. Sjögren syndrome and pregnancy. Tokai Exp Clin Med 1991; 16: 83-8. Cerca con Google

101. Mosca M, Neri R, Strigini F, Carmignani A, Totti D, Tavoni A, Bombardieri S. Pregnancy outcome in patients with undifferentiated connective tissue disease: a preliminary study on 25 pregnancies. Lupus 2002; 11: 304-307. Cerca con Google

102. Brucato A, Buyon JP, Horsfall AC, Lee LA, Reichlin M. Fourth international workshop on neonatal lupus syndromes and the Ro/SSA-La/SSB System. Clinical & Experimental Rheumatology 1999; 17(1):130-136. Cerca con Google

103. Colombo G, Brucato A, Coluccio E, Compasso S, Luzzana C, Franceschini F, Quinzanini M, Scorza R. DNA typing of maternal HLA in congenital complete heart block: comparison with systemic lupus erythematosus and primary Sjogren's syndrome. Arthritis & Rheumatism 1999; 42(8):1757-1764. Cerca con Google

104. Grava C, Ruffatti A, Milanesi O, Favaro M, Tonello M, Calligaro a, Del Ross T, Todesco S. Isolated congenital heart block in undifferentiated connective tissue disease and in primari Sjogrn’s sindrome: a clinical study of 81 pregnancies in 41 patients. Reumatismo. 2005; 57 (3): 180-6. Cerca con Google

105. Saleeb S, Copel J, Friedman D, Buyon JP. Comparison of treatment with fluorinated glucocorticoids to the natural history of autoantibody-associated congenital heart block: retrospective review of the research registry for neonatal lupus. Arthritis & Rheumatism 1999; 42(11):2335-2345. Cerca con Google

106. Brucato A, Gasparini M, Vignati G, Riccobono S, De Juli E, Quinzanini M, Bortolan C, Coluccio E, Massari D. Isolated congenital complete heart block: longterm outcome of children and immunogenetic study. J Rheumatol 1995; 22(3):541-543. Cerca con Google

107. Cimaz R, Stramba-Badiale M, Brucato A, Catelli L, Panzeri P, Meroni PL. QT interval prolongation in asymptomatic anti-SSA/Ro-positive infants without congenital heart block. Arthritis & Rheumatism 2000; 43(5):1049-1053. Cerca con Google

108. Brucato A, Cimaz R, Catelli L, Meroni P. Anti-Ro-associated sinus bradycardia in newborns [letter]. Circulation 2000; 102(11):E88-E89. Cerca con Google

109. Gerosa M, Cimaz R, Stramba-Badiale M, Golene K, Meregalli E, Trepidi L, Acaia B, Cattaneo R, Tincani A, Motta M, Doria A, Zulian F, Milanesi O, Brucato A, Ribaldi P, Meroni PL. Rheumatology. 2007; 46:1285-9. Cerca con Google

110. Udink ten Cate FE, Breur JM, Cohen MI, Boramanand N, Kapusta L, Crosson JE, Brenner JL, Leibbers LJ, Friedman AH, Velter VL, Meijboom EJ. Dilated cardiomyopathy in isolated congenital complete atrioventricular block: early and longterm risk in children. J Am Coll Cardiol 2001; 37(4):1129-1134. Cerca con Google

111. Zuppa AA, Fracchiolla A,Cota F, Gallini F, Savarese I, D’Andrea V, Luciano R, Romagnoli C. Infants born to mothers with anti-SSA/Ro autoantibodies: neonatal outcome and follow-up. Clin Pediatr (Phila) 2007; Dec 5. Cerca con Google

112. Motta M, Rodriguez-Perez C, Tincani A, Lojacono A, Chirico G. Outcome of infants from mothers with anti-SSA/Ro antibodies. J Perinatol. 2007; 27(5): 278-83. Cerca con Google

113. Neiman AR, Lee LA, Weston WL, Buyon JP. Cutaneous manifestations of neonatal lupus without heart block: Characteristics of mothers and children enrolled in a national registry. J Pediatr 2000; 137(5):674-680. Cerca con Google

114. Buyon JP, Clancy RM. Dying right to live longer: positing apoptosis as a link between maternal autoantibodies and congenital heart block. Lupus. 2008; 17: 86-90. Cerca con Google

115. Boutjdir M, Chen L, Zhang ZH, Tseng CE, DiDonato F, Rashbaum W, Morris A, el.Sherig N, Buyon JP. Arhythmogenicity of IgG and anti-52-kD SSA/Ro affinitypurified antibodies from mothers of children with congenital heart block. Circ Res 1997; 80(3):354-362. Cerca con Google

116. Xiao GQ, Hu K, Boutjdir M. Direct inhibition of expressed cardiac l- and t-type calcium channels by igg from mothers whose children have congenital heart block. Circulation 2001; 103(11):1599-1604. Cerca con Google

117. Miranda-Carus ME, Askanase AD, Clancy RM, Di Donato F, Chou TM, Libera MR, Chan EK, Buyon JP. Anti-SSA/Ro and anti-SSB/La autoantibodies bind the surface of apoptotic fetal cardiocytes and promote secretion of TNF-alpha by macrophages. J Immunol 2000; 165(9):5345-5351. Cerca con Google

118. Friedman DM, Kim MY, Copel JA, Davis C, Phoon CK, Glickstein JS, Buyon JP. Utilità of cardiac monitorimg in fetuses at risk for congenital heart block: the PR interval and Dexamethasone evaluation (PRIDE) prospective study. Circulation. 2008;117 (4): 485-93. Cerca con Google

119. Costedoat-Chalumeau N, Amoura Z, Le Thi Hong D, Georgin S, Vauthier D, Sebbouh D, Francés C, Villain E, Wechsler B, Piette J-C. Neonatal lupus sindrome: review of the literature. La revue de Médicine interne. 2003; 24: 659-671. Cerca con Google

120. Brucato A, Frassi M, Franceschini F, Cimaz R, Faden D, Pisoni MP, Muscara M, Vignati G, Stramba-Badiale M, Catelli L, Lojacono A, Cavazzana I, Ghirardello A, Vescovi F, Gambari PF, Doria A, Meroni PL, Tincani A. Risk of congenital complete heart block in newborns of mothers with anti-Ro/SSA antibodies detected by counterimmunoelectrophoresis: a prospective study of 100 women. Arthritis Rheum2001; 44(8):1832-1835. Cerca con Google

121. Frassi M, Brucato A, Cavazzana I, Franceschini F, Faden D, Motta M, Doria A, Cimaz R, Pisoni MP, Muscarà M, Castellino G, Brambilla G, Meroni PL, Cattaneo R, Biasini Rebaioli C, Antonioli C, Balestrieri G, Tincani A. Neonatal lupus: clinical features and risk of congenital cardiac heart block in newborns from mothers with anti Ro/SSA antibodies. Reumatismo. 2001; 53 (4): 298-304. Cerca con Google

122. Arnett FC, Edworthy SM, Bloch DA, McShare DJ, Fries JF, Cooper NS, Kealey NA, Kaplan SR, Liang MM, Luthra HS. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid artrhitis. Arthritis Rheum 1998; 31: 315-24. Cerca con Google

123. Gambari PF, Doria A, Todesco S. Criteri diagnostici e classificativi del lupus eritematoso sistemico. Reumatismo 1993; 45(supp 3): 18-21. Cerca con Google

124. Masi AT, Rodnan GP, Medsger et al. Preliminary criteria for the classification of systemic sclerosis (scleroderma). Bull Rheum Dis 1981; 31: 1-6. Cerca con Google

125. Bohan A, Peter JD. Polimyositis and dermatomyositis. N Engl J Med 1975; 13: 344- 407. Cerca con Google

126. Vitali C, Bombardieri S, Moutsopoulos HM et al. Preliminary criteria for the classification of Sjögren’s syndrome. Arthritis Rheum 1993; 36: 340-7. Cerca con Google

127. Johnson MJ. Obstetric complications and rheumaatic disease. Rheum Dis Clin N Am 1997; 23: 63-182. Cerca con Google

128. Russel AS, Johnston C, Chew C, Maksymowych WP. Evidence for reduced Th1 function in normal pregnancy : a hipothesis for the remission of rheumatoid arthritis. J Rheumatol 1997; 24: 1045-50. Cerca con Google

129. Ramsey-Goldman R. The effect of pregnancy on the vasculitides. Scand J Rheumatol 1998; 27 (Suppl 107): 116-7. Cerca con Google

130. Stten VD. Scleroderma and pregnancy. Rheum Dis Clin N Am 1997; 23: 133-47. Cerca con Google

131. Ruiz-Irastorza G, Alves J, Khamashta MA et al. Increased rate of lupus flare during pregnancy and the puerperium: a prospective study of pregnancies. Br J Rheumatol 1996; 35: 133-8. Cerca con Google

132. Petri M, Hopkins Lupus Pregnancy Center: 1987 to 1996. Rheum Dis Clin North Am 1997; 23: 1-13. Cerca con Google

133. Ruiz-Irastorza G, Khamashta M, Hughes GRV. Does SLE flare during pregnancy? Scand J Rheumatol 1998; 27 (Suppl 107): 76-9. Cerca con Google

134. Subcommittee for Scleroderma Criteria of the American Rheumatism Association Diagnostic and Therapeutic Criterion Committee: preliminary criteria for the classification of the systemic lupus sclerosis (scleroderma). Arthritis Rheum 1980; 23: 581-90. Cerca con Google

135. Bohan A, Peter JB. Polymyositis and dermatomyositis. Part II. New Engl J Med 1965; 292: 403-7. Cerca con Google

136. Asherson RA, Khamasha MA, Ordi-Ros J et al. The “primary” antiphospholipid syndrome: major clinical and serological features. Medicine (Baltimore) 1989; 68: 366- 74. Cerca con Google

137. Skomsvoll JF, Ostensen M, Irgens LM, Baste V. Obstetrical and neonatal outcome in pregnant patients with rheumatic diseases. Scan J Rheumatol 1998; 27 (Suppl. 107): 109-12. Cerca con Google

138. Mascola MA, Repke JT. Obstetric management of the high-risk lupus pregnancy. Rheum Dis Clin N Am 1997; 23: 119-35. Cerca con Google

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