Zampieri, S. and Ghirardello, A. and Doria, A. and van Venrooij, WH. and Raats, JMH. (2001) Recombinant anti-P proteins antibodies isolated from human autoimmune library: reactivity, specificity and epitope recognition. [Online journal papers]
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The ribosomal phosphoproteins P0, P1 and P2 are targeted by autoantibodies in SLE. The presence in the patient sera of the anti-P antibodies is highly specific for the disease and correlates with psychiatric, renal and liver involvement. In order to better characterize these autoantibodies (reactivity, specificity and epitope recognition), recombinant anti-P monoclonal antibodies were isolated from an human SLE patient derived phage display library.
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