New therapeutical strategies are needed to face the dramatic increases in the prevalence of difficult to heal ulcers. Using new in vivo models and a wound staging system developed ad hoc, in these studies we propose an important role of mechanical forces as non pharmacological healing inductors. Results demonstrate that controlled regimens of mechanical forces in vivo may be used to stimulate cell proliferation and vascular remodeling, alone or in combination with more traditional approaches based on soluble factors and extracellular matrices.
Integrazione di forze meccaniche, fattori circolanti e matrici extracellulari: un nuovo paradigma in ingegneria dei tessuti / Pietramaggiori, Giorgio. - (2007 Sep 01).
Integrazione di forze meccaniche, fattori circolanti e matrici extracellulari: un nuovo paradigma in ingegneria dei tessuti
Pietramaggiori, Giorgio
2007
Abstract
New therapeutical strategies are needed to face the dramatic increases in the prevalence of difficult to heal ulcers. Using new in vivo models and a wound staging system developed ad hoc, in these studies we propose an important role of mechanical forces as non pharmacological healing inductors. Results demonstrate that controlled regimens of mechanical forces in vivo may be used to stimulate cell proliferation and vascular remodeling, alone or in combination with more traditional approaches based on soluble factors and extracellular matrices.File | Dimensione | Formato | |
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