Vai ai contenuti. | Spostati sulla navigazione | Spostati sulla ricerca | Vai al menu | Contatti | Accessibilità

| Crea un account

Eleftheriou, Georgios (2008) Uso di farmaci Antidepressivi Inbitori del Reuptake della Serotonina, di farmaci Antiepilettici e di Retinoidi in Gravidanza. [Tesi di dottorato]

Full text disponibile come:

[img]Documento PDF
464Kb

Abstract (inglese)

After the catastrophic event of thalidome in Europe, early in the sixties, the FDA planed experimental protocols for the study of the reproduction toxicity of drugs and other substances.
In this work, we begun our route from the fecundation to the normal fetal development and the principles of developmental toxicology. We reported an outline of the pathogenesis of developmental toxicity and we mentioned the sources of the teratogenic evaluation: animal experiments and epidemiologic data.
Finally, we refer the follow-up interview; this interview consisted of a comprehensive list of questions with regard to maternal health during pregnancy, pregnancy outcome, delivery, and neonatal health.


Statistiche Download - Aggiungi a RefWorks
Tipo di EPrint:Tesi di dottorato
Relatore:Carrara, Marisa
Dottorato (corsi e scuole):Ciclo 20 > Corsi per il 20simo ciclo > FARMACOLOGIA E TOSSICOLOGIA, TERAPIA RIANIMATIVA E INTENSIVA
Data di deposito della tesi:2008
Anno di Pubblicazione:2008
Parole chiave (italiano / inglese):GRAVIDANZA, FARMACOVIGILANZA, CITALOPRAM, ISOTRETINOINA, ANTIEPILETTICI
Settori scientifico-disciplinari MIUR:Area 06 - Scienze mediche > MED/41 Anestesiologia
Struttura di riferimento:Dipartimenti > Dipartimento di Farmacologia ed Anestesiologia "E. Meneghetti"
Codice ID:578
Depositato il:22 Set 2008
Simple Metadata
Full Metadata
EndNote Format

Bibliografia

I riferimenti della bibliografia possono essere cercati con Cerca la citazione di AIRE, copiando il titolo dell'articolo (o del libro) e la rivista (se presente) nei campi appositi di "Cerca la Citazione di AIRE".
Le url contenute in alcuni riferimenti sono raggiungibili cliccando sul link alla fine della citazione (Vai!) e tramite Google (Ricerca con Google). Il risultato dipende dalla formattazione della citazione.

1. Abdulrazzaq YM, Bastaki SM, Padmanabhan R: Teratogenic effects of vigabatrin in TO mouse fetuses. Teratology. 1997;55(3):165-76. Cerca con Google

2. ACOG (American College of Obstetrics and Gynecology) Technical Bulletin N° 182: Depression in women: Int J Gynecol Obstet 1993; 43:203-11. Cerca con Google

3. Adams J, Vorhees CV, Middaugh LD: Developmental neurotoxicity of anticonvulsants: human and animal evidence on phenytoin. Neurotoxicol Teratol. 1990;12(3):203-14. Cerca con Google

4. Adams J: Structure-activity and dose-response relationships in the neural and behavioral teratogenesis of retinoids. Neurotoxicol Teratol. 1993;15(3):193-202. Cerca con Google

5. Addis A, Bonati M, Sch?ler L, Moretti ME, Koren G. Teratogen information services around the world. In: Koren G ed. Maternal-fetal toxicology. 3rd ed. New York, NY: Marcel Dekker Inc; 2001. pag 733-45. Cerca con Google

6. Addis A, Koren G. Safety of fluoxetine during the first trimester of pregnancy: a meta-analytical review of epidemiological studies. Psychol Med. 2000;30(1):89-94. Cerca con Google

7. AIFA 2005: Ministero della salute. Agenzia Italiana del Farmaco (AIFA). Farmaci e gravidanza. La valutazione del rischio teratogeno basata su prove di efficacia. Roma: AIFA; 2005. Cerca con Google

8. Almond S, Logan RFL: Carotenemia. Br Med J 1942;2:239. Cerca con Google

9. Altshuler LL, Cohen LS, Moline ML, Kahn DA, Carpenter D, Docherty JP, Ross RW: Treatment of depression in women: summary of the expert consensus guidelines.J Psych Pract. 2001;7(3):185- 208. Cerca con Google

10. Alwan A, Reefhuis J, Rasmussen S, Olney R, Friedman JM: Maternal use of selective serotonin reuptake inhibitors and risk for birth defects. 45th annual conference of the Teratology Society meeting, St Pete Beach, Florida, June 25-30, 2005. [Abstract]. Cerca con Google

11. Annegers JF, Baumgartner KB, Hauser WA, Kurland LT: Epilepsy, antiepileptic drugs, and the risk of spontaneous abortion. Epilepsia. 1988;29(4):451-8. Cerca con Google

12. Ardinger HH, Atkin JF, Blackston RD, Elsas LJ, Clarren SK, Livingstone S, Flannery DB, Pellock JM, Harrod MJ, Lammer EJ, Majewski F, Schinzel A, Toriello HV, Hanson JW: Verification of the fetal valproate syndrome phenotype. Am J Med Genet. 1988;29(1):171-85. Cerca con Google

13. Armenti VT, Johnson EM: Effects of maternal hypervitaminosis A on perinatal rat lung histology. Biol Neonate. 1979;36(5-6):305-10. Cerca con Google

14. Arnhold T, Elmazar MMA, Nau H: Prevention of vitamin A teratogenesis by phytol or phytanic acid results from reduced metabolism of retinol to the teratogenic metabolite, all-trans-retinoic acid. Toxicol Sci 2002;6(2):274-282. Cerca con Google

15. Arpino C, Brescianini S, Robert E, Castilla EE, Cocchi G, Cornel MC, de Vigan C, Lancaster PA, Merlob P, Sumiyoshi Y, Zampino G, Renzi C, Rosano A, Mastroiacovo P: Teratogenic effects of antiepileptic drugs: use of an International Database on Malformations and Drug Exposure (MADRE). Epilepsia. 2000;41(11):1436- 43. Cerca con Google

16. ARS (Agricultural Research Service): Overview of the 2005 U.S. Dietary Guidelines for Americans. September 22, 2005. Department of Health and Human Services (HHS) and Department of Agriculture (USDA). Dietary Guidelines Advisory Committee (DGAC) report 2005. Cerca con Google

17. Asselineau D, Cavey MT, Shroot B, Darmon M. Control of epidermal differentiation by a retinoid analogue unable to bind to cytosolic retinoic acid-binding proteins (CRABP). J Invest Dermatol. 1992;98(2):128-34. Cerca con Google

18. Atanackovic G, Koren G: Fetal exposure to oral isotretinoin: failure to comply with the Pregnancy Prevention Program. CMAJ. 1999;160(12):1719-20. Cerca con Google

19. Auckland G: A case of carotinemia. Br Med J 1952;2:267. Cerca con Google

20. Auerbach JG, Hans SL, Marcus J, Maeir S: Maternal psychotropic medication and neonatal behavior. Neurotoxicol Teratol. 1992;14(6):399-406. Cerca con Google

21. Autret E, Berjot M, Jonville-Bera AP, Aubry MC, Moraine C: Anophthalmia and agenesis of optic chiasma associated with adapalene gel in early pregnancy.Lancet. 1997;350(9074):339. Cerca con Google

22. Autret E, Radal M, Jonville-Bera AP, Goehrs JM: Isotretinoin (Roaccutane) in women of childbearing age: failure of following prescription guidelines. Ann Dermatol Venereol. 1997;124(8):518-22. Cerca con Google

23. Baldwin, J.A., Davidson E.J., Pritchard A.L, Ridings, J.E: The reproductive toxicology of paroxetine. Acta Psychiatr. Scand. 1989 ;80 (37):39. Cerca con Google

24. Barbero P, Lotersztein V, Bronberg R, Perez M, Alba L: Acitretin embryopathy: A case report. Birth Defects Res A Clin Mol Teratol 2004;70(10):831-833. Cerca con Google

25. Battaglia FC, Lubchenco LO. A practical classification of newborn infants by weight and gestational age. J Pediatr. 1967; 71(2):159-63. Cerca con Google

26. Bauernfeind JC. The safe use of vitamin A. A report of the International Vitamin A Consultative Group (IVACG). Washington, DC: The Nutrition Foundation, 1982. Cerca con Google

27. Bellantuono C, Migliarese G, Gentile S: Serotonin reuptake inhibitors in pregnancy and the risk of major malformations: a systematic review. Hum Psychopharmacol. 2007;22(3):121-8. Cerca con Google

28. Ben David S, Einarson T, Ben David Y, Nulman I, Pastuszak A, Koren G. The safety of nitrofurantoin during the first trimester of pregnancy: meta-analysis. Fundam Clin Pharmacol. 1995;9(5):503-7. Cerca con Google

29. Bennett GD, Amore BM, Finnell RH, Wlodarczyk B, Kalhorn TF, Skiles GL, Nelson SD, Slattery JT: Teratogenicity of carbamazepine-10, 11-epoxide and oxcarbazepine in the SWV mouse. J Pharmacol Exp Ther. 1996;279(3):1237-42. Cerca con Google

30. Bérard A, Azoulay L, Koren G, Blais L, Perreault S, Oraichi D: Isotretinoin, pregnancies, abortions and birth defects: a population-based perspective. Br J Clin Pharmacol. 2007;63(2):196-205. Cerca con Google

31. Bérard A, Ramos E, Rey E, Blais L, St-André M, Oraichi D. First trimester exposure to paroxetine and risk of cardiac malformations in infants: the importance of dosage. Birth Defects Res B Dev Reprod Toxicol. 2007;80(1):18-27 Cerca con Google

32. Bernhardt IB, Dorsey DJ. Hypervitaminosis A and congenital renal anomalies in a human infant. Obstet Gynecol. 1974; 43(5):750-5. Cerca con Google

33. Bocciolone L, Parazzini F. L’epidemiologia dell’aborto spontaneo: una revisione della letteratura. Ann Ostet Ginecol Med Perinat 1989;CX:323-34. Cerca con Google

34. Bologa M, Tang B, Klein J, Tesoro A, Koren G. Pregnancy-induced changes in drug metabolism in epileptic women. J Pharmacol Exp Ther. 1991 May;257(2):735-40. Cerca con Google

35. Bonari L, Pinto N, Ahn E, Einarson A, Steiner M, Koren G: Perinatal risks of untreated depression during pregnancy. Can J Psychiatry. 2004;49(11):726-35. Cerca con Google

36. Bonati M, Nannini S, Addis A: Vitamin A supplementation during pregnancy in developed countries. Lancet 1995; 345 (8951):736-7. Cerca con Google

37. Botto LD, Khoury MJ, Mulinare J, Erickson JD: Periconceptional multivitamin use and the occurrence of conotruncal heart defects: results from a population-based, case-control study. Pediatrics. 1996;98(5): 911-7. Cerca con Google

38. Botto LD, Loffredo C, Scanlon KS, Ferencz C, Khoury MJ, Wilson PD, Correa A: Vitamin A and cardiac outflow tract defects. Epidemiology 2001;12(5):491-496. Cerca con Google

39. Bracken MB. Oral contraception and congenital malformations in offspring: a review and metaanalysis of the prospective studies. Obstet Gynecol. 1990;76(3 Pt 2):552-7. Cerca con Google

40. Briggs GG, Freeman RK, Yaffe SJ: Drugs in pregnancy and lactation 6th Edition. Philadelphia, PA; Lippincot Williams & Wilkins eds. 2002; Cerca con Google

41. Brown NA, Shull G, Fabro S. Assessment of the teratogenic potential of trimethadione in the CD-1 mouse. Toxicol Appl Pharmacol. 1979;51(1):59-71. Cerca con Google

42. Bruno MK, Harden CL: Epilepsy in Pregnant Women. Curr Treat Options Neurol. 2002;4(1):31- 40. Cerca con Google

43. Burtin P, Taddio A, Ariburnu O, Einarson TR, Koren G. Safety of metronidazole in pregnancy: a meta-analysis. Am J Obstet Gynecol. 1995;172(2 Pt 1):525-9. Cerca con Google

44. Byrd, R.A., Brophy, GT, Markham, JK: Developmental toxicology studies of fluoxetine hydrochloride (I) administered orally to rats and rabbits. Teratology 1989; 39:P67. Cerca con Google

45. Byrne B. Epilepsy and pregnancy. Ir Med J. 1997;90(5):172. Cerca con Google

46. Cerca con Google

47. Caldwell AP, Seegmiller RE: Evaluation of the teratogenic potential of topically applied all-trans retinoic acid (RA) in mice. Teratology 1991; 43(5):443. Cerca con Google

48. Camera G, Pregliasco P: Ear malformation in baby born to mother using tretinoin cream. (letter) Lancet 1992;339(8794):687. Cerca con Google

49. Canger R, Battino D, Canevini MP, Fumarola C, Guidolin L, Vignoli A, Mamoli D, Palmieri C, Molteni F, Granata T, Hassibi P, Zamperini P, Pardi G, Avanzini G. Malformations in offspring of women with epilepsy: a prospective study. Epilepsia 1999; 40(9):1231-1236. Cerca con Google

50. Cantu JM, Garcia-Cruz D. Midline facial defect as a teratogenic effect of metronidazole. Birth Cerca con Google

51. Defects Orig Artic Ser. 1982;18(3 Pt A):85-8. Cerca con Google

52. Capita R, Alonso-Calleja C: Intake of nutrients associated with an increased risk of cardiovascular disease in a Spanish population. Int J Food Sci Nutr. 2003 Jan;54(1):57-75. Cerca con Google

53. Caro-Paton T, Carvajal A, Martin de Diego I, Martin-Arias LH, Alvarez Requejo A, Rodriguez Pinilla E. Is metronidazole teratogenic? A meta-analysis. Br J Clin Pharmacol. 1997;44(2):179-82. Cerca con Google

54. Chambers CD, Hernandez-Diaz S, Van Marter LJ, Werler MM, Louik C, Jones KL, Mitchell AA. Selective serotonin-reuptake inhibitors and risk of persistent pulmonary hypertension of the newborn. N Engl J Med. 2006; 354(6):579-87. Cerca con Google

55. Chambers CD, Johnson KA, Dick LM, Felix RJ, Jones KL. Birth outcomes in pregnant women taking fluoxetine. N Engl J Med. 1996;335(14):1010-5. Cerca con Google

56. Chan A, Hanna M, Abbott M, Keane RJ: Oral retinoids and pregnancy. Med J Aust. 1996;165(3):164-7. Cerca con Google

57. Chandraratna RA. Tazarotene: the first receptor- selective topical retinoid for the treatment of psoriasis. Am Acad Dermatol 1997;37(2 Pt 3):S12-7. Cerca con Google

58. Chen C, Jensen BK, Mistry G, Wyss R, Zultak M, Patel IH, Rakhit AK: Negligible systemic absorption of topical isotretinoin cream: implications for teratogenicity. J Clin Pharmacol 1997; 37(4):279-84. Cerca con Google

59. Christian MS, Mitala JJ, Powers WJ Jr, McKenzie BE, Latriano L: A developmental toxicity study of tretinoin emollient cream (Renova) applied topically to New Zealand white rabbits. J Am Acad Dermatol. 1997;36(3 Pt 2):S67-76. Cerca con Google

60. Clark KE, Harrington DJ: Effect of prostacyclin synthetase inhibitor tranylcypromine on uterine blood flow in pregnancy. Prostaglandins 1982;23(2):227-36. Cerca con Google

61. Cohen LS, Altshuler LL, Harlow BL, Nonacs R, Newport DJ, Viguera AC, Suri R, Burt VK, Hendrick V, Reminick AM, Loughead A, Vitonis AF, Stowe ZN. Relapse of major depression during pregnancy in women who maintain or discontinue antidepressant treatment. JAMA. 2006;295(5):499-507. Cerca con Google

62. Cohen LS, Heller VL, Bailey JW, Grush L, Ablon JS, Bouffard SM. Birth outcomes following prenatal exposure to fluoxetine. Biol Psychiatry 2000; 48(10):996-1000. Cerca con Google

63. Cohlan SQ. Congenital anomalies in the rat produced by excessive intake of vitamin A during pregnancy. Pediatrics. 1954;13(6):556-67. Cerca con Google

64. Colley SM, Walpole I, Fabian VA, Kakulas BA: Topical tretinoin and fetal malformations. Med J Aust. 1998;168(9):467. Cerca con Google

65. Commission of the European Communities: Nutrient and energy intakes for the European Community, Reports of the Scientific Committee for Food, thirty first series, Office for Official Publications of the European Communities, Luxembourg, 1993. Cerca con Google

66. Costei AM, Kozer E, Ho T, Ito S, Koren G. Perinatal outcome following third trimester exposure to paroxetine. Arch Pediatr Adolesc Med. 2002; 156 (11): 1129-1132. Cerca con Google

67. Cunnington M, Tennis P; International Lamotrigine Pregnancy Registry Scientific Advisory Committee: Lamotrigine and the risk of malformations in pregnancy. Neurology. 2005;64(6):955- 60. Cerca con Google

68. Czeizel A, Racz J. Evaluation of drug intake during pregnancy in the Hungarian Case-Control Surveillance of Congenital Anomalies. Teratology. 1990;42(5):505-12. Cerca con Google

69. Czeizel A. Lack of evidence of teratogenicity of benzodiazepine drugs in Hungary. Reprod Toxicol. 1987-1988;1(3):183-8. Cerca con Google

70. Czeizel AE, Rockenbauer M. A population based case-control teratologic study of oral metronidazole treatment during pregnancy.Br J Obstet Gynaecol. 1998;105(3):322-7. Cerca con Google

71. Czeizel AE, Rockenbauer M: Prevention of congenital abnormalities of vitamin A. Int J Vitam Nutr Res 1998;68(4): 219-31. Cerca con Google

72. Dagadu M, Gillman J: Hypercarotenaemia in Ghanaians. Lancet. 1963;1:531-2. Cerca con Google

73. Dai WS, Hsu MA, Itri LM: Safety of pregnancy after discontinuation of isotretinoin. Arch Dermatol. 1989;125(3):362-5. Cerca con Google

74. Dai WS, LaBraico JM, Stern RS: Epidemiology of isotretinoin exposure during pregnancy. J Am Acad Dermatol. 1992;26(4):599-606. Cerca con Google

75. Danielsson BR, Danielson K, Tomson T. Phenytoin causes phalangeal hypoplasia in the rabbit fetus at clinically relevant free plasma concentrations. Teratology. 1995;52(5):252-9. Cerca con Google

76. Davies TS, Kluwe WM: Preclinical toxicological evaluation of sertraline hydrochloride. Drug Chem Toxicol, 1998; 21(4):521-537. Cerca con Google

77. De Die-Smulders CEM, Sturkenboom MCJM, Veraart J, van Katwijk C, Sastrowijoto P, van der Linden E: Severe limb defects and craniofacial anomalies in a fetus conceived during acitretin therapy. Teratology 1995;52:215-219. Cerca con Google

78. De Wals P, Bloch D, Calabro A, Calzolari E, Cornel MC, Johnson Z, Ligutic I, Nevin N, Pexieder T, Stoll C, Tenconi R, Tilmont P. Association between holoprosencephaly and exposure to topical retinoids: results of the EUROCAT survey. Paediatr Perinatal Epidemiol 1991;5:445-447. Cerca con Google

79. DeBuys LR: Some clinical experience with carotenemia. Trans Mississippi State Med Assoc 1923;56:133. Cerca con Google

80. Delgado-Escueta AV, Janz D: Consensus guidelines: preconception counseling, management, and care of the pregnant woman with epilepsy. Neurology. 1992;42(4 Suppl 5):149-60. Cerca con Google

81. Diav-Citrin O, Shechtman S, Ornoy S, Arnon J, Schaefer C, Garbis H, Clementi M, Ornoy A: Safety of haloperidol and penfluridol in pregnancy: a multicenter, prospective, controlled study.J Clin Psychiatry. 2005;66(3):317-22. Cerca con Google

82. Diav-Citrin O, Shechtman S, Weinbaum D, Arnon J, Di Gianantonio E, Clementi M, Ornoy A: Paroxetine and fluoxetine in pregnancy: a multicenter, prospective, controlled study. 16th annual conference of the ENTIS meeting, Haarlem, Seprember 3-7, 2005. [Abstract]. Cerca con Google

83. DiLiberti JH, Farndon PA, Dennis NR, Curry CJ: The fetal valproate syndrome. Am J Med Genet. 1984; 19(3):473-81. Cerca con Google

84. Dolovich LR, Addis A, Vaillancourt JM, Power JD, Koren G, Einarson TR. Benzodiazepine use in pregnancy and major malformations or oral cleft: meta-analysis of cohort and case-control studies. BMJ. 1998;317(7162):839-43. Cerca con Google

85. Dudas I, Czeizel AE: Use of 6,000 IU vitamin A during early pregnancy without teratogenic effect. Teratology 1992;45:335-336. Cerca con Google

86. Ehlers K, Sturje H, Merker HJ, Nau H: Valproic acid-induced spina bifida: a mouse model. Teratology. 1992;45(2):145-54. Cerca con Google

87. Einarson TR, Einarson A. Newer antidepressants in pregnancy and rates of major malformations: a meta-analysis of prospective comparative studies. Pharmacoepidemiol Drug Saf. 2005; Cerca con Google

88. ENTIS: 18th annual ENTIS meeting, Helsinki, 8-10th June, 2007. Cerca con Google

89. Ericson A, Kallen B, Wiholm B. Delivery outcome after the use of antidepressants in early pregnancy. Eur J Clin Pharmacol. 1999;55(7):503-8. Cerca con Google

90. Eros E, Czeizel AE, Rockenbauer M, Sorensen HT, Olsen J: A population-based case-control teratologic study of nitrazepam, medazepam, tofisopam, alprazolum and clonazepam treatment during pregnancy. Eur J Obstet Gynecol Reprod Biol. 2002;101(2):147-54. Cerca con Google

91. Evans K, Hickey-Dwyer MU: Cleft anterior segment with maternal hypervitaminosis A. Br J Ophthalmol. 1991;75(11):691-2. Cerca con Google

92. FAO/WHO Joint Expert Consultation. Requirements of vitamin A, iron, folate and vitamin B12. FAO Food and Nutrition series N° 23, 1988. FAO, Rome Italy. Cerca con Google

93. Finnell RH, Abbott LC, Taylor SM. The fetal hydantoin syndrome: answers from a mouse model. Reprod Toxicol. 1989;3(2):127-33. Cerca con Google

94. Finnell RH, Dansky LV. Parental epilepsy, anticonvulsant drugs, and reproductive outcome: epidemiologic and experimental findings spanning three decades; 1: Animal studies. Reprod Toxicol. 1991;5(4):281-99. Cerca con Google

95. Fiorino F. “FA.VI.G.”: proposta di un sistema nazionale di farmacovigilanza in gravidanza. Atti del LXXI Congresso Nazionale S.I.G.O. Palermo, CoFeSe Edizioni, 1995, 181-188. Cerca con Google

96. Fonda Allen JF, Rosenbaum KN: Counseling after exposure to excessive amounts of beta-carotene in the first trimester: a case report. Teratology. 1992;45(5):459-460. Cerca con Google

97. French J, Edrich P, Cramer JA: A systematic review of the safety profile of levetiracetam: a new antiepileptic drug. Epilepsy Res. 2001;47(1-2):77-90. Cerca con Google

98. Freytag TL, Morris JG: Chronic administration of excess vitamin A in the domestic cat results in low teratogenicity. FASEB J 1997;11(3):A412. Cerca con Google

99. Fried S, Kozer E, Nulman I, Einarson TR, Koren G. Malformation rates in children of women with untreated epilepsy: a meta-analysis. Drug Saf. 2004;27(3):197-202. Cerca con Google

100. Garcia-Fernandez RA, Perez-Martinez C, Escudero-Diez A, Garcia-Iglesias MJ: Effects of retinoic acid exposure in utero on mouse vibrissal follicle development. Anat Histol Embryol. 2000;29(4):207-10. Cerca con Google

101. Geiger JM, Baudin M, Saurat JH: Teratogenic risk with etretinate and acitretin treatment. Dermatology. 1994;189(2):109-16. Cerca con Google

102. Golabi M, Hall B D, Clericuzio C, Johnston K: Fetal primidone syndrome: a distinct pattern of malformations. (Abstract) Am. J. Hum. Genet. 1985; 37: A54. Cerca con Google

103. Goldbohm RA, Brants HA, Hulshof KF, van den Brandt PA: The contribution of various foods to intake of vitamin A and carotenoids in The Netherlands. Int J Vitam Nutr Res. 1998;68(6):378-83. Cerca con Google

104. Goldstein DJ, Corbin LA, Sundell KL. Effects of first-trimester fluoxetine exposure on the newborn. Obstet Gynecol. 1997;89(5 Pt 1):713-8. Cerca con Google

105. Goldstein DJ. Effects of third trimester fluoxetine exposure on the newborn. J Clin Psychopharmacol. 1995; 15(6):417-20. Cerca con Google

106. Gracia CR, Sammel MD, Chittams J, Hummel AC, Shaunik A, Barnhart KT. Risk factors for spontaneous abortion in early symptomatic first-trimester pregnancies. Obstet Gynecol. 2005;106(5 Pt 1):993-9. Cerca con Google

107. Granstrom G, Kullaa-Mikkonen A: Experimental craniofacial malformations induced by retinoids and resembling branchial arch syndromes. Scand J Plast Reconstr Surg Hand Surg. 1990;24(1):3- 12. Cerca con Google

108. Gregg NM: Congenital cataract following German Measles in the mother. Transactions of the ophthalmologcal Society of Australia 1941; 3: 35-46. Cerca con Google

109. Grote W, Harms D, Janig U, Kietzmann H, Ravens U, Schwarze I: Malformation of fetus conceived 4 months after termination of maternal etretinate treatment. Lancet. 1985;1(8440):1276. Cerca con Google

110. Hale F: The Relation of Vitamin A to the Eye Development in the Pig. Am. Soc. Anim. Prod. 1935:126-128. Cerca con Google

111. Hallberg P, Sjoblom V: The use of selective serotonin reuptake inhibitors during pregnancy and breast-feeding: a review and clinical aspects.J Clin Psychopharmacol. 2005;25(1):59-73. Cerca con Google

112. Hatch EE, Palmer JR, Titus-Ernstoff L, Noller KL, Kaufman RH, Mittendorf R, Robboy SJ, Hyer M, Cowan CM, Adam E, Colton T, Hartge P, Hoover RN. Cancer risk in women exposed to diethylstilbestrol in utero. JAMA. 1998;280(7):630-4. Cerca con Google

113. Hathcock JN, Hattan DG, Jenkins MY, McDonald JT, Sundaresan PR, Wilkening VL: Evaluation of vitamin A toxicity. Am J Clin Nutr. 1990;52(2):183-202. Cerca con Google

114. Hauser WA, Tomson T: Lamotrigine and the risk of malformations in pregnancy. Neurology. 2006;66 (1):153-4. Cerca con Google

115. Hayes WC, Cobel-Geard SR, Hanley TR Jr, Murray JS, Freshour NL, Rao KS, John JA: Teratogenic effects of vitamin A palmitate in Fischer 344 rats. Drug Chem Toxicol. 1981;4:283-95. Cerca con Google

116. Health Council/Food and Nutrition Council: Vitamin A and teratogenicity. The Hague, The Netherlnads, 1994. Cerca con Google

117. Heckel S, Favre R, Weber P, Dellenbach P. Teratogenicity of retinoids. A case and review of the literature. J Gynecol Obstet Biol Reprod (Paris). 1993;22(1):43-7. Cerca con Google

118. Heckel S, Favre R, Weber P, Dellenbach P: Teratogenicity of retinoids. A case and review of the literature. J Gynecol Obstet Biol Reprod (Paris). 1993;22(1):43-7. Cerca con Google

119. Heinonen M: Food groups as the source of retinoids, carotenoids, and vitamin A in Finland. Int J Vitam Nutr Res. 1991;61(1):3-9. Cerca con Google

120. Hemels ME, Einarson A, Koren G, Lanctot KL, Einarson TR. Antidepressant use during pregnancy and the rates of spontaneous abortions: a meta-analysis. Ann Pharmacother. 2005;39(5):803-9. Cerca con Google

121. Hendrick V, Smith LM, Suri R, Hwang S, Haynes D, Altshuler L. Birth outcomes after prenatal exposure to antidepressant medication. Am J Obstet Gynecol. 2003; 188(3):812-5. Cerca con Google

122. Hendrickx AG, Nau H, Binkerd P, Rowland JM, Rowland JR, Cukierski MJ, Cukierski MA. Valproic acid developmental toxicity and pharmacokinetics in the rhesus monkey: an interspecies comparison. Teratology. 1988;38(4):329-45. Cerca con Google

123. Hendrickx AG, Peterson P, Hartmann D, Hummler H: Vitamin A teratogenicity and risk assessment in the macaque retinoid model. Reprod Toxicol 2000;14(4):311-23. Cerca con Google

124. Herbst AL. Behavior of estrogen-associated female genital tract cancer and its relation to neoplasia following intrauterine exposure to diethylstilbestrol (DES). Gynecol Oncol. 2000;76(2):147-56. Cerca con Google

125. Hernandez-Diaz S, Werler MM, Walker AM, Mitchell AA: Folic acid antagonists during pregnancy and the risk of birth defects. N Engl J Med. 2000;343(22):1608-14. Cerca con Google

126. Heywood R, Palmer AK, Gregson RL, Hummler H: The toxicity of beta-carotene. Toxicology. 1985;36(2-3):91-100. Cerca con Google

127. Holmes LB, Harvey EA, Coull BA, Huntington KB, Khoshbin S, Hayes AM, Ryan LM: The teratogenicity of anticonvulsant drugs. N Engl J Med. 2001;344(15):1132-8. Cerca con Google

128. Holmes LB, Wyszynski DF, Baldwin EJ, Habecker E, Glassman LH, Smith CR: Increased risk for non-syndromic cleft palate among infants exposed to lamotrigine during pregnancy (abstract). Teratology Society, 46th Annual Meeting, June 24-29, 2006, Tucson, Arizona. Cerca con Google

129. Hummler H, Korte R, Hendrickx AG: Induction of malformations in the cynomolgus monkey with 13-cis retinoic acid. Teratology. 1990;42(3):263-72. Cerca con Google

130. Huot C, Gauthier M, Lebel M, Larbrisseau A: Congenital malformations associated with maternal use of valproic acid. Can J Neurol Sci. 1987;14(3):290-3. Cerca con Google

131. Hutchings DE, Gaston J: The effects of vitamin A excess administered during the mid-fetal period on learning and development in rat offspring. Dev Psychobiol. 1974;7(3):225-33. Cerca con Google

132. Iqbal MM, Gundlapalli SP, Ryan WG, Ryals T, Passman TE: Effects of antimanic moodstabilizing drugs on fetuses, neonates, and nursing infants. South Med J. 2001;94(3):304-22. Cerca con Google

133. Isoherranen N, Spiegelstein O, Bialer M, Zhang J, Merriweather M, Yagen B, Roeder M, Triplett AA, Schurig V, Finnell RH. Developmental outcome of levetiracetam, its major metabolite in humans, 2-pyrrolidinone N-butyric acid, and its enantiomer ®-alpha-ethyl-oxo-pyrrolidine acetamide in a mouse model of teratogenicity. Epilepsia. 2003;44(10):1280-8. Cerca con Google

134. Jaiswal S, Coombs RC, Isbister GK: Paroxetine withdrawal in a neonate with historical and laboratory confirmation. Eur J Pediatr 2003;162(10):723-724. Cerca con Google

135. Jick SS, Terris BZ, Jick H: First trimester topical tretinoin and congenital disorders. Lancet. 1993;341(8854):1181-2. Cerca con Google

136. Jick SS, Terris BZ: Anticonvulsants and congenital malformations. Pharmacotherapy. 1997;17(3):561-4. Cerca con Google

137. Johnson EM: A risk assessment of topical tretinoin as a potential human developmental toxin based on animal and comparative human data. J Am Acad Dermatol. 1997;36(3 Pt 2):S86-90. Cerca con Google

138. Jones KL, Lacro RV, Johnson KA, Adams J: Pattern of malformations in the children of women treated with carbamazepine during pregnancy. N Engl J Med. 1989;320(25):1661-6. Cerca con Google

139. Kaaja E, Kaaja R, Hiilesmaa V: Major malformations in offspring of women with epilepsy. Neurology. 2003;60 (4):575-9. Cerca con Google

140. Kallen B: Restriction of the use of drugs with teratogenic properties: Swedish experiences with isotretinoin. Teratology 1999;60:53. Cerca con Google

141. Kalousek DK, Barrett IJ, Gartner AB. Spontaneous abortion and confined chromosomal mosaicism. Hum Genet. 1992;88(6):642-6. Cerca con Google

142. Kalra S, Born L, Sarkar M, Einarsonrn A: The safety of antidepressant use in pregnancy. Expert Opin Drug Saf. 2005;4(2):273-84. Cerca con Google

143. Kamm JJ: Toxicology, carcinogenicity, and teratogenicity of some orally administered retinoids. J Am Acad Dermatol. 1982;6(4 Pt 2 Suppl):652-9. Cerca con Google

144. Cerca con Google

145. Kaneko S, Battino D, Andermann E, Wada K, Kan R, Takeda A, Nakane Y, Ogawa Y, Avanzini G, Fumarola C, Granata T, Molteni F, Pardi G, Minotti L, Canger R, Dansky L, Oguni M, Lopes- Cendas I, Sherwin A, Andermann F, Seni MH, Okada M, Teranishi T. Congenital malformations due to antiepileptic drugs. Epilepsy Res. 1999;33(2-3):145-58. Cerca con Google

146. Kaneko S, Otani K, Kondo T, Fukushima Y, Nakamura Y, Ogawa Y et al: Malformation in infants of mothers with epilepsy receiving antiepileptic drugs. Neurology. 1992; 42 (4 Suppl 5):68-74. Cerca con Google

147. Kapoor S, Kapoor M. Congenital ocular anomalies in Pondicherry. J Pediatr Ophthalmol. 1977;14(6):382-9. Cerca con Google

148. Kinney DK, Yurgelun-Todd DA, Levy DL, Medoff D, Lajonchere CM, Radford-Paregol M: Obstetrical complications in patients with bipolar disorder and their siblings. Psychiatry Res. 1993;48(1):47-56. Cerca con Google

149. Kistler A, Hummler H: Teratogenesis and reproductive safety evaluation of the retinoid etretin (Ro 10-1670). Arch Toxicol 1985;58(1):50-6. Cerca con Google

150. Klemetti A, Saxen L: Prospective versus retrospective approach in the search for environmental causes of malformations. Am J Public Health 1967; 57(12): 2071-2075. Cerca con Google

151. Koch S, Gopfert-Geyer I, Jager-Roman E, Jakob S, Huth H, Hartmann A, Rating D, Helge H. Antiepileptic agents during pregnancy. A prospective study on the course of pregnancy, malformations and child development. Dtsch Med Wochenschr. 1983;108(7):250-7. Cerca con Google

152. Kochhar DM, Penner JD, Minutella LM: Biotransformation of etretinate and developmental toxicity of etretin and other aromatic retinoids in teratogenesis bioassays. Drug Metab Dispos 1989;17(6):618-624. Cerca con Google

153. Kochhar DM, Penner JD, Tellone CI: Comparative teratogenic activities of two retinoids: effects on palate and limb development. Teratog Carcinog Mutagen. 1984;4(4):377-87. Cerca con Google

154. Kochhar DM, Penner JD: Developmental effects of isotretinoin and 4 oxo-isotretinoin: the role of metabolism in teratogenicity. Teratology 1987;36:67-75. Cerca con Google

155. Kochhar DM, Satre MA: Retinoids and fetal malformations. In: Sharma RP (ed). Dietary Factors and Birth Defects. San Francisco, Calif.: Pacific Division AAAS, 1993, pp 134-229. Cerca con Google

156. Kochhar DM. Teratogenic activity of retinoic acid. Acta Pathol Microbiol Scand. 1967;70:398-404. Cerca con Google

157. Koren G, Florescu A, Costei AM, Boskovic R, Moretti ME. Nonsteroidal antiinflammatory drugs during third trimester and the risk of premature closure of the ductus arteriosus: a meta-analysis. Ann Pharmacother. 2006;40(5):824-9. Cerca con Google

158. Kozma C: Valproic acid embryopathy: report of two siblings with further expansion of the phenotypic abnormalities and a review of the literature. Am J Med Genet. 2001;98(2):168-75. Cerca con Google

159. Kraft JC, Bui T, Juchau MR: Elevated levels of all-trans-retinoic acid in cultured rat embryos 1.5 hr after intraamniotic microinjections with 13-cis-retinoic acid or retinol and correlations with dysmorphogenesis. Biochem Pharmacol. 1991;42(12):R21-4. Cerca con Google

160. Kubota Y, Shimotake T, Iwai N: Congenital anomalies in mice induced by etretinate. Eur J Pediatr Surg. 2000;10(4):248-51. Cerca con Google

161. Kulin NA, Pastuszak A, Sage SR, Schick-Boschetto B, Spivey G, Feldkamp M, Ormond K, Matsui D, Stein-Schechman AK, Cook L, Brochu J, Rieder M, Koren G: Pregnancy outcome following maternal use of the new selective serotonin reuptake inhibitors: a prospective controlled multicenter study. JAMA. 1998; 279(8):609-10. Cerca con Google

162. Kwasigroch TE, Bullen M: Effects of isotretinoin (13-cis-retinoic acid) on the development of mouse limbs in vivo and in vitro. Teratology 1991;44:605-616. Cerca con Google

163. Laine K, Heikkinen T, Ekblad U, Kero P: Effects of exposure to selective serotonin reuptake inhibitors during pregnancy on serotonergic symptoms in newborns and cord blood monoamine and prolactin concentrations. Arch Gen Psychiatry 2003;60(7):720-726. Cerca con Google

164. Lammer EJ, Chen DT, Hoar RM, Agnish ND, Benke PJ, Braun JT, Curry CJ, Fernhoff PM, Grix AW Jr, Lott IT, Richard JM, Sun SC. Retinoic acid embryopathy. N Engl J Med. 1985;313(14):837-41. Cerca con Google

165. Lammer EJ, Hayes AM, Schunior A, Holmes LB. Risk for major malformation among human fetuses exposed to isotretinoin (13-cis-retinoic acid). Teratology 1987;35:68A. Cerca con Google

166. Lenz W, Knapp K: Thalidomide embryopathy. Arch Environ Health. 1962;5:100-5. Cerca con Google

167. Leppik IE, Gram L, Deaton R, Sommerville KW: Safety of tiagabine: summary of 53 trials. Epilepsy Res. 1999;33(2-3):235-46. Cerca con Google

168. Lindhout D, Meinardi H, Meijer S.J.A, Nau H: Antiepileptic drugs and teratogenesis in two consecutive cohorts: Changes in prescription policy paralleled by changes in pattern of malformations. Neurology 1992; 42(Suppl 5):94-110. Cerca con Google

169. Lindhout D, Meinardi H: Spina bifida and in-utero exposure to valproate. Lancet. 1984;2(8399):396. Cerca con Google

170. Lipson AH, Collins F, Webster WS: Multiple congenital defects associated with maternal use of topical tretinoin. Lancet 1993;341(8856):1352-3. Cerca con Google

171. Little AB: There's many a slip 'twixt implantation and the crib. N Engl J Med. 1988;319(4):241-2. Cerca con Google

172. Ljunger E, Cnattingius S, Lundin C, Anneren G: Chromosomal anomalies in first-trimester miscarriages. Acta Obstet Gynecol Scand. 2005;84(11):1103-7. Cerca con Google

173. Lofberg B, Chahoud I, Bochert G, Nau H: Teratogenicity of the 13-cis and all-trans-isomers of the aromatic retinoid etretin: correlation to transplacental pharmacokinetics in mice during organogenesis after a single oral dose. Teratology 1990;41:707-716. Cerca con Google

174. Long L: Levetiracetam monotherapy during pregnancy. Epilepsy Behav. 2003;4(4):447-8. Cerca con Google

175. Lorente CA, Miller SA: Vitamin A induction of cleft palate. Cleft Palate J. 1978;15(4):378-85. Cerca con Google

176. Loureiro KD, Kao KK, Jones KL, Alvarado S, Chavez C, Dick L, Felix R, Johnson D, Chambers CD: Minor malformations characteristic of the retinoic acid embryopathy and other birth outcomes in children of women exposed to topical tretinoin during early pregnancy. Am J Med Genet A. 2005;136 (2):117-21. Cerca con Google

177. Lowenstein EJ: Isotretinoin made S.M.A.R.T. and simple. Cutis. 2002;70(2):115-20. Cerca con Google

178. Cerca con Google

179. Majewski F, Steger M, Richter B, Gill J, Rabe F. The teratogenicity of hydantoins and barbiturates in humans, with considerations on the etiology of malformations and cerebral disturbances in the children of epileptic parents. Int J Biol Res Pregnancy. 1981;2(1):37-45. Cerca con Google

180. Malone FD, D’Alton ME: Drugs in pregnancy: anticonvul-sants. Semin Perinatol. 1997;21:114-23. Cerca con Google

181. Maradit H, Geiger JM: Potential risk of birth defects after acitretin discontinuation. Dermatology. 1999;198(1):3-4. Cerca con Google

182. Marchi NS, Azoubel R, Tognola WA. Teratogenic effects of lamotrigine on rat fetal brain: a morphometric study. Arq Neuropsiquiatr. 2001;59(2-B):362-4. Cerca con Google

183. Marcus SM, Barry KL, Flynn HA, Tandon R, Greden JF. Treatment guidelines for depression in pregnancy. Int J Gynaecol Obstet. 2001;72(1):61-70. Cerca con Google

184. Marshall H, Studer M, Popperl H, Aparicio S, Kuroiwa A, Brenner S, Krumlauf R: A conserved retinoic acid response element required for early expression of the homeobox gene Hoxb-1. Nature. 1994;370 (6490):567-71. Cerca con Google

185. Martinez-Frias ML, Salvador J: Epidemiological aspects of prenatal exposure to high doses of vitamin A in Spain. Eur J Epidemiol. 1990;6(2):118-23. Cerca con Google

186. Martinez-Frias ML, Salvador J: Megadose vitamin A and teratogenicity. Lancet. 1988;1(8579):236. Cerca con Google

187. Mastroiacovo P, Mazzone T, Addis A, Elephant E, Carlier P, Vial T, Garbis H, Robert E, Bonati M, Ornoy A, Finardi A, Schaffer C, Caramelli L, Rodriguez-Pinilla E, Clementi M: High vitamin A intake in early pregnancy and major malformations: a multicenter prospective controlled study. Teratology. 1999;59(1):7-11. Cerca con Google

188. Mastroiacovo, P; Botto, LD & Castilla, E: I registri delle malformazioni congenite: una valutazione critica. Prospettive in pediatria 1994; 24:227-233. Cerca con Google

189. Mathews-Roth MM: Lack of genotoxicity with beta-carotene. Toxicol Lett. 1988;41(3):185-91. Cerca con Google

190. McConaghy RMS: Carotenaemia. Lancet 1952; 2:714. Cerca con Google

191. McElhatton PR, Garbis HM, Elefant E, Vial T, Bellemin B, Mastroiacovo P, Arnon J, Rodriguez- Pinilla E, Schaefer C, Pexieder T, Merlob P, Dal Verme S: The outcome of pregnancy in 689 women exposed to therapeutic doses of antidepressants. A collaborative study of the European Network of Teratology Information Services (ENTIS). Reprod Toxicol. 1996;10(4):285-94. Cerca con Google

192. Meischenguiser R, D’Giano CH, Ferraro SM: Oxcarbazepine in pregnancy: clinical experience in Argentina. Epilepsy Behav. 2004;5(2):163-7. Cerca con Google

193. Menter A: Pharmacokinetics and safety of tazarotene. J Am Acad Dermatol 2000;43(2 Pt 3):S31- S35. Cerca con Google

194. Merks JH, van Karnebeek CD, Caron HN, Hennekam RC. Phenotypic abnormalities: terminology and classification. Am J Med Genet A. 2003;123(3):211-30. Cerca con Google

195. Miller RK, Hendrickx AG, Mills JL, Hummler H, Wiegand UW: Periconceptional vitamin A use: how much is teratogenic? Reprod-Toxicol. 1998; 12(1): 75-88 Cerca con Google

196. Mills JL, Simpson JL, Cunningham GC, Conley MR, Rhoads GG: Vitamin A and birth defects. Am J Obstet Gynecol 1997;177(1):31-36. Cerca con Google

197. Monga M: Vitamin A and its congeners. Semin Perinatol. 1997;21(2):135-42. Cerca con Google

198. Montouris G: Gabapentin exposure in human pregnancy: results from the Gabapentin Pregnancy Registry. Epilepsy Behav. 2003;4(3):310-7. Cerca con Google

199. Montouris G: Safety of the newer antiepileptic drug oxcarbazepine during pregnancy. Curr Med Res Opin. 2005;21(5):693-701. Cerca con Google

200. Mooney MP, Hoyenga KT, Hoyenga KB, Morton JRC: Prenatal hypervitaminosis A and postnatal behavioral development in the rat. Neurobehav Toxicol Teratol 1981;3(1):1-4. Cerca con Google

201. Morinobu T, Tamai H, Murata T, Manago M, Takenaka H, Hayashi K, Mino M: Changes in betacarotene levels by long-term administration of natural beta-carotene derived from Dunaliella bardawil in humans. J Nutr Sci Vitaminol (Tokyo). 1994;40(5):421-30. Cerca con Google

202. Morrell MJ: The new antiepileptic drugs and women: efficacy, reproductive health, pregnancy, and fetal outcome. Epilepsia. 1996;37 Suppl 6:S34-44. Cerca con Google

203. Morrison DG, Elsas FJ, Descartes M: Congenital oculomotor nerve synkinesis associated with fetal retinoid syndrome. J AAPOS. 2005;9(2):166-8. Cerca con Google

204. Morrow J, Russell A, Guthrie E, Parsons L, Robertson I, Waddell R, Irwin B, McGivern RC, Morrison PJ, Craig J: Malformation risks of antiepileptic drugs in pregnancy: a prospective study from the UK Epilepsy and Pregnancy Register. J Neurol Neurosurg Psychiatry. 2006;77(2):193-8. Cerca con Google

205. Mounoud RL, Klein D, Weber F: A case of Goldenhar syndrome: acute vitamin A intoxication in Cerca con Google

206. the mother during pregnancy. J Genet Hum. 1975;23(2):135-54. Cerca con Google

207. MRC Vitamin Study Research Group (1991). Prevention of neural tube defects: results of the Medical Research Council Vitamin Study (1991). The Lancet, 1991;338(8760):131-7. Cerca con Google

208. Mueller-Kueppers M. On the problem of fetal damage during pregnancy caused by intake of anticonvulsants. Acta Paedopsychiatr. 1963;30:401-5. Cerca con Google

209. Mulder EJ, Robles de Medina PG, Huizink AC, Van den Bergh BR, Buitelaar JK, Visser GH: Prenatal maternal stress: effects on pregnancy and the child. Early Hum Dev. 2002;70(1-2):3-14. Cerca con Google

210. Mulder GB, Manley N, Grant J, Schmidt K, Zeng W, Eckhoff C, Maggio Price L: Effects of excess vitamin A on development of cranial neural crest-derived structures: a neonatal and embryologic study. Teratology 2000;62:214-226. Cerca con Google

211. Nau H, Hauck RS, Ehlers K: Valproic acid-induced neural tube defects in mouse and human: aspects of chirality, alternative drug development, pharmacokinetics and possible mechanisms. Pharmacol Toxicol. 1991;69(5):310-21. Cerca con Google

212. Nau H: Embryotoxicity and teratogenicity of topical retinoic acid. Skin Pharmacol. 1993;(6):35-44. Cerca con Google

213. Navarre-Belhassen C, Blancehet P, Hillaire-Buys D, Sarda P, Blayac J-P: Multiple congenital malformations associated with topical tretinoin. Ann Pharmacother. 1998;32(4):505-6. Cerca con Google

214. Nelson MM, Forfar JO: Associations between drugs administered during pregnancy and congenital abnormalities of the fetus. Br Med J. 1971;1(5748):523-7. Cerca con Google

215. Newman CG: Teratogen update: clinical aspects of thalidomide embryopathy: a continuing preoccupation. Teratology. 1985;32(1):133-44. Cerca con Google

216. Newman CG: The thalidomide syndrome: risks of exposure and spectrum of malformations. Clin Cerca con Google

217. Perinatol. 1986;13(3):555-73. Cerca con Google

218. Nora JJ, Nora AH, Blu J, Ingram J, Fountain A, Peterson M, Lortscher RH, Kimberling WJ. Exogenous progestogen and estrogen implicated in birth defects. JAMA. 1978;240(9):837-43. Cerca con Google

219. Nulman I, Rovet J, Stewart DE, Wolpin J, Gardner HA, Theis JG, Kulin N, Koren G. Neurodevelopment of children exposed in utero to antidepressant drugs. N Engl J Med. 1997;336(4):258-62. Cerca con Google

220. Nulman I, Scolnik D, Chitayat D, Farkas LD, Koren G: Findings in children exposed in utero to phenytoin and carbamazepine monotherapy: independent effects of epilepsy and medications. Am J Med Genet. 1997;68(1):18-24. Cerca con Google

221. O'Brien MM, Kiely M, Harrington KE, Robson PJ, Strain JJ, Flynn A: The North/South Ireland Food Consumption Survey: vitamin intakes in 18-64-year-old adults. Public Health Nutr. 2001;4(5A):1069-79. Cerca con Google

222. Ogawa Y, Kaneko S, Otani K, Fukushima Y: Serum folic acid levels in epileptic mothers and their relation-ship to congenital malformations. Epilepsy Res. 1991;8(1):75-8. Cerca con Google

223. Olsen J, Basso O: Reproductive Epidemiology. In: Ahrens W, Pigeot J (eds.): Handbook of Epidemiology; 2005, XII: 1043-1111. Springer Verlag. Cerca con Google

224. Omtzigt JG, Los FJ, Grobbee DE, Pijpers L, Jahoda MG, Brandenburg H, Stewart PA, Gaillard HL, Sachs ES, Wladimiroff JW, Lindhout D: The risk of spina bifida aperta after first-trimester exposure to valproate in a prenatal cohort. Neurology. 1992;42(4 Suppl 5):119-25. Cerca con Google

225. Ornoy A, Cohen E: Outcome of children born to epileptic mothers treated with carbamazepine during pregnancy. Arch Dis Child. 1996;75(6):517-20. Cerca con Google

226. Osborn JF, Cattaruzza MS, Spinelli A: Risk of spontaneous abortion in Italy, 1978-1995, and the effect of maternal age, gravidity, marital status, and education. Am J Epidemiol. 2000;151(1):98- 105. Cerca con Google

227. Padmanabhan R, Abdulrazzaq YM, Bastaki SM, Shafiullah M, Chandranath SI. Experimental studies on reproductive toxicologic effects of lamotrigine in mice. Birth Defects Res B Dev Reprod Toxicol. 2003; 68 (5):428-38. Cerca con Google

228. Padmanabhan R, Singh G, Singh S: Malformations of the eye resulting from maternal hypervitaminosis A during gestation in the rat. Acta Anat (Basel). 1981;110(4):291-8. Cerca con Google

229. Pastuszak AL, Schuler L, Speck-Martins CE, Coelho KE, Cordello SM, Vargas F, Brunoni D, Schwarz IV, Larrandaburu M, Safattle H, Meloni VF, Koren G: Use of misoprostol during pregnancy and Mobius’ syndrome in infants. N Engl J Med. 1998;338(26):1881-5. Cerca con Google

230. Cerca con Google

231. Petkovich M, Brand NJ, Krust A, Chambon P. human retinoic acid receptor which belongs to the family of nuclear receptors.Nature. 1987;330(6147):444-50. Cerca con Google

232. Petrere JA, Anderson JA. Developmental toxicity studies in mice, rats, and rabbits with the anticonvulsant gabapentin. Fundam Appl Toxicol. 1994;23(4):585-9. Cerca con Google

233. Pogenberg V, Guichou JF, Vivat-Hannah V, Kammerer S, Pérez E, Germain P, de Lera AR, Gronemeyer H, Royer CA, Bourguet W. Characterization of the interaction between retinoic acid receptor/retinoid X receptor (RAR/RXR) heterodimers and transcriptional coactivators through structural and fluorescence anisotropy studies J Biol Chem. 2005;280(2):1625-33. Cerca con Google

234. Polifka JE, Dolan CR, Donlan MA, Friedman JM. Clinical teratology counseling and consultation report: high dose beta-carotene use during early pregnancy. Teratology. 1996;54(2):103-7. Cerca con Google

235. Preti A, Cardascia L, Zen T, Pellizzari P, Marchetti M, Favaretto G, Miotto P: Obstetric complications in patients with depression. A population-based case-control study.J Affect Disord. 2000;61(1-2):101-6. Cerca con Google

236. Rahimi R, Nikfar S, Abdollahi M. Pregnancy outcomes following exposure to serotonin reuptake inhibitors: a meta-analysis of clinical trials. Reprod Toxicol. 2006;22(4):571-5. Cerca con Google

237. Raman-Wilms L, Tseng AL, Wighardt S, Einarson TR, Koren G. Fetal genital effects of firsttrimester sex hormone exposure: a meta-analysis. Obstet Gynecol. 1995;85(1):141-9. Cerca con Google

238. Regan L, Rai R. Epidemiology and the medical causes of miscarriage. Bailliere’s Clin Obstet Gynaecol 2000;14: 839-54. Cerca con Google

239. Rizzo R, Lammer EJ, Parano E, Pavone L, Argyle JC: Limb reduction defects in humans associated with prenatal isotretinoin exposure. Teratology 1991;44:599-604. Cerca con Google

240. Robboy SJ, Young RH, Welch WR, Truslow GY, Prat J, Herbst AL, Scully RE. Atypical vaginal adenosis and cervical ectropion. Association with clear cell adenocarcinoma in diethylstilbestrolexposed offspring. Cancer. 1984;54(5):869-75. Cerca con Google

241. Roche Laboratories, Nutley, NJ, 2000: Product Information: Accutane(R), Isotretinoin. Cerca con Google

242. Ronsmans C, Campbell O, Collumbien M: Effect of supplementation with vitamin A or beta carotene on mortality related to pregnancy. Slight modifications in definitions could alter interpretation of results. BMJ. 1999;319(7218):1202-3. Cerca con Google

243. Rosa F: Holoprosencephaly and antiepileptic exposures. Teratology. 1995;51(4):230. Cerca con Google

244. Rosa FW, Wilk AL, Kelsey FO: Teratogen update: vitamin A congeners.Teratology. 1986;33(3):355-64. Cerca con Google

245. Rosa FW. Teratogenicity of isotretinoin. Lancet. 1983;2(8348):513. Cerca con Google

246. Rosa FW: Spina bifida in infants of women treated with carbamazepine during pregnancy. N Engl J Med 1991;324(10):674-677. Cerca con Google

247. Rosen RC, Lightner ES. Phenotypic malformations in association with maternal trimethadione therapy. J Pediatr. 1978;92(2):240-4. Cerca con Google

248. Rosenberg L, Mitchell AA, Parsells JL, Pashayan H, Louik C, Shapiro S. Lack of relation of oral clefts to diazepam use during pregnancy.N Engl J Med. 1983;309(21):1282-5. Cerca con Google

249. Rothman KJ, Moore LL, Singer MR, Nguyen US, Mannino S, Milunsky A: Teratogenicity of high vitamin A intake. N Engl J Med. 1995;333(21):1369-73. Cerca con Google

250. Rubin JD, Ferencz C, Loffredo C. Use of prescription and non-prescription drugs in pregnancy. The Baltimore-Washington Infant Study Group. J Clin Epidemiol. 1993;46(6):581-9. Cerca con Google

251. Russell AJ, Macpherson H, Cairnie V, Brodie MJ: The care of pregnant women with epilepsy: a survey of obstetricians in Scotland. Seizure. 1996;5(4):271-7. Cerca con Google

252. Saba A, Turrini A, Mistura G, Cialfa E & Vichi M: Indagine nazionale sui consumi alimentari delle famiglie 1980-84 - alcuni principali risultati. Riv. Soc. It. Sci. Alim. 1990; 19 (4): 53-65. Cerca con Google

253. Sabers A, Dam M, A-Rogvi-Hansen B, Boas J, Sidenius P, Laue Friis M, Alving J, Dahl M, Ankerhus J, Mouritzen Dam A:Epilepsy and pregnancy: lamotrigine as main drug used. Acta Neurol Scand. 2004; 109(1):9-13. Cerca con Google

254. Sachdev HP: Effect of supplementation with vitamin A or beta carotene on mortality related to pregnancy. No magic pills exist for reducing mortality related to pregnancy. BMJ. 1999;319(7218):1202. Cerca con Google

255. Sacker A, Done DJ, Crow TJ: Obstetric complications in children born to parents with schizophrenia: a meta-analysis of case-control studies. Psychol Med. 1996;26 (2):279-87. Cerca con Google

256. Saito H, Kobayashi H, Takeno S, Sakai T. Fetal toxicity of benzodiazepines in rats. Res Commun Cerca con Google

257. Chem Pathol Pharmacol. 1984;46(3):437-47. Cerca con Google

258. Samren EB, van Duijn CM, Christiaens GC, Hofman A, Lindhout D. Antiepileptic drug regimens and major congenital abnormalities in the offspring. Ann Neurol. 1999;46(5):739-46. Cerca con Google

259. Samren EB, van Duijn CM, Koch S, Hiilesmaa VK, Klepel H, Bardy AH, Mannagetta GB, Deichl AW, Gaily E, Granstrom ML, Meinardi H, Grobbee DE, Hofman A, Janz D, Lindhout D. Maternal use of antiepileptic drugs and the risk of major congenital malformations: a joint European prospective study of human teratogenesis associated with maternal epilepsy. Epilepsia. 1997;38(9):981-90. Cerca con Google

260. Saxen I, Saxen L. Letter: Association between maternal intake of diazepam and oral clefts. Lancet. 1975;2(7933):498. Cerca con Google

261. Schardein JL. Congenital abnormalities and hormones during pregnancy: a clinical review. Teratology. 1980;22(3):251-70. Cerca con Google

262. Schardein JL: Chemically Induced Birth Defects, 3rd ed. New York, MarcDekker, Inc, 2000 p. 184 Cerca con Google

263. Schmidt D, Kramer G: The new anticonvulsant drugs. Implications for avoidance of adverse effects. Drug Saf. 1994;11(6):422-31. Cerca con Google

264. Schofield C, Stewart J, Wheeler E: The diets of pregnant and post-pregnant women in different social groups in London and Edinburgh: calcium, iron, retinol, ascorbic acid and folic acid. Br J Nutr. 1989;62(2):363-77. Cerca con Google

265. Schorry EK, Oppenheimer SG, Saal HM: Valproate embryopathy: clinical and cognitive profile in 5 siblings. Am J Med Genet A. 2005; 133(2):202-6. Cerca con Google

266. Seip M: Growth retardation, dysmorphic facies and minor malformations following massive exposure to phenobarbitone in utero. Acta Paediatr Scand. 1976; 65(5):617-21. Cerca con Google

267. Selcen D, Seidman S, Nigro MA: Otocerebral anomalies associated with topical tretinoin use. Brain Dev 2000;22(4):218-20. Cerca con Google

268. Seller MJ, Adinolfi M: The curly-tail mouse: an experimental model for human neural tube defects. Life Sci. 1981;29(16):1607-15. Cerca con Google

269. Shapiro L, Pastuszak A, Curto G, Koren G: Safety of first-trimester exposure to topical tretinoin: prsospective cohort study. Lancet 1997;350(9085): 1143-1144. Cerca con Google

270. Shaw GM, Velie EM, Schaffer D, Lammer EJ: Periconceptional intake of vitamin A among women and risk of neural tube defect-affected pregnancies. Teratology 1997;55:132-133. Cerca con Google

271. Shenefelt RE: Gross congenital malformations. Animal model: treatment of various species with a large dose of vitamin A at known stages in pregnancy. Am J Pathol. 1972;66(3):589-92. Cerca con Google

272. Shenefelt, R.E.: Morphogenesis of malformations in hamsters caused by retinoic acid. Relation to dose and stage of treatment. Teratology 1972;5(1):103-18. Cerca con Google

273. Simon GE, Cunningham ML, Davis RL. Outcomes of prenatal antidepressant exposure. Am J Psychiatry. 2002;159 (12):2055-61. Cerca con Google

274. Simpson JL, Mills JL, Morey A, Metzger BE, Knopp RH, Holmes LB, Jovanovic-Peterson L, Aarons JH, Brown Z, Van Allen M, Elias S: Drug ingestion during pregnancy: infrequent exposure in a contemporary United States sample. National Institute of Child Health and Human Development Diabetes in Early Pregnancy Study Group. Am J Perinatol. 1989;6(2):244-51. Cerca con Google

275. Simpson JL: Incidence and timing of pregnancy losses: relevance to evaluating safety of early prenatal diagnosis. Am J Med Genet. 1990;35(2):165-73. Cerca con Google

276. Singh JD: Palm oil induced congenital anomalies in rats. Senten Ijo 1980; 20:139-142. Cerca con Google

277. Smithells RW: Epidemiology of malformations: inspiration and perspiration. Teratology. 1974;10(3):217-20. Cerca con Google

278. Solomons NW, Bulux J: Effects of nutritional status on carotene uptake and bioconversion. Ann NY Acad Sci. 1993;691:96-109. Cerca con Google

279. Stephens TD, Fillmore BJ: Hypothesis: thalidomide embryopathy-proposed mechanism of action. Teratology. 2000;61(3):189-95. Cerca con Google

280. Stephens TD: Proposed mechanisms of action in thalidomide embryopathy. Teratology. 1988;38(3):229-39. Cerca con Google

281. Stern RS, Rosa F, Baum C: Isotretinoin and pregnancy. J Am Acad Dermatol. 1984;10(5 Pt 1):851- 4. Cerca con Google

282. Stockard, CR. Developmental rate and structural expression. Am. Jour. Anat 1921;28: 115-277. Cerca con Google

283. Strickler SM, Dansky LV, Miller MA, Seni MH, Andermann E, Spielberg SP: Genetic predisposition to phenytoin-induced birth defects. Lancet. 1985;2 (8458): 746-9. Cerca con Google

284. Studer M, Popperl H, Marshall H, Kuroiwa A, Krumlauf R: Role of a conserved retinoic acid response element in rhombomere restriction of Hoxb-1. Science. 1994;265(5179):1728-32. Cerca con Google

285. Sturkenboom MC, de Jong-Van Den Berg LT, van Voorst-Vader PC, Cornel MC, Stricker BH, Wesseling H: Inability to detect plasma etretinate and acitretin is a poor predictor of the absence of these teratogens in tissue after stopping acitretin treatment. Br J Clin Pharmacol. 1994;38:229-35. Cerca con Google

286. Sulik KK, Cook CS, Webster WS. Teratogens and craniofacial malformations: relationships to cell death. Development. 1988;103 Suppl:213-31. Cerca con Google

287. Sulik KK, Dehart DB: Retinoic-acid-induced limb malformations resulting from apical ectodermal ridge cell death. Teratology. 1988;37(6):527-37. Cerca con Google

288. Cerca con Google

289. Sullivan FM, McElhatton PR. Teratogenic activity of the antiepileptic drugs phenobarbital, phenytoin, and primidone in mice. Toxicol Appl Pharmacol. 1975;34(2):271-82. Cerca con Google

290. ten Berg K, Samren EB, van Oppen AC, Engelsman M, Lindhout D: Levetiracetam use and pregnancy outcome. Reprod Toxicol. 2005;20(1):175-8. Cerca con Google

291. Tennis P, Eldridge RR: International Lamotrigine Pregnancy Registry Scientific Advisory Committee: Preliminary results on pregnancy outcomes in women using lamotrigine. Epilepsia. 2002;43(10):1161-7. Cerca con Google

292. Teratology Society. Position paper: Recommendations for vitamin A use during pregnancy. Teratology 1987; 35:269-75. Cerca con Google

293. Theodosis DT, Fraser FC: Early changes in the mouse neuroepithelium preceding exencephaly induced by hypervitaminosis A. Teratology. 1978;18(2):219-32. Cerca con Google

294. Turton JA, Willars GB, Haselden JN, Ward SJ, Steele CE, Hicks RM.: Comparative teratogenicity of nine retinoids in the rat. Int J Exp Pathol 1992; 73(5):551-63. Cerca con Google

295. Tzimas G, Burgin H, Collins MD, Hummler H, Nau H: The high sensitivity of the rabbit to the teratogenic effects of 13-cis-retinoic acid (isotretinoin) is a consequence of prolonged exposure of the embryo to 13-cis-retinoic acid and 13-cis-4-oxo-retinoic acid, and not of isomerization to alltrans- retinoic acid. Arch Toxicol. 1994;68(2):119-28. Cerca con Google

296. Tzimas G, Collins MD, Burgin H, Hummler H, Nau H: Embryotoxic doses of vitamin A to rabbits result in low plasma but high embryonic concentrations of all-trans-retinoic acid: risk of vitamin A exposure in humans. J Nutr 1996;126:2159-2171. Cerca con Google

297. Vacca L, Hutchings DE: Effect of maternal vitamin A excess on S-100 in neonatal rat cerebellum: a preliminary study. Dev Psychobiol. 1977;10(2):171-6. Cerca con Google

298. Vajda FJ, Hitchcock A, Graham J, Solinas C, O’brien TJ, Lander CM, Eadie MJ: Foetal malformations and seizure control: data of the Australian Pregnancy Registry. Eur J Neurol. 2006;13(6):645-54. Cerca con Google

299. Van Hoogdalem EJ: Transdermal absorption of topical anti-acne agents in man; review of clinical pharmacokinetic data. J Eur Acad Dermatol Venereol. 1998;11 Suppl 1:S13-9. Cerca con Google

300. Vandrie DM, Puri S, Upton RT, DeMeester LJ: Adenosquamous carcinoma of the cervix in a woman exposed to diethylstilbestrol in utero. Obstet Gynecol. 1983;61(3 Suppl):84S-87S. Cerca con Google

301. Velisek L, Veliskova J, Etgen AM, Stanton PK, Moshe SL: Region-specific modulation of limbic seizure susceptibility by ovarian steroids. Brain Res. 1999;842(1):132-8. Cerca con Google

302. Veliskova J, Velisek L, Galanopoulou AS, Sperber EF: Neuroprotective effects of estrogens on hippocampal cells in adult female rats after status epilepticus. Epilepsia. 2000;41 Suppl 6:S30-5. Cerca con Google

303. Vila Ceren C, Demestre Guasch X, Raspall Torrent F, Elizari Saco MJ, Sala Castellvi P, Martinez Nadal S: Topiramate and pregnancy. Neonate with bone anomalies. An Pediatr (Barc). 2005;63(4):363-5. Cerca con Google

304. Von Lennep E, El Khazen N, De Pierreux G, Amy JJ, Rodesch F, Van Regemorter N: A case of partial sirenomelia and possible vitamin A teratogenesis. Prenat Diagn. 1985;5(1):35-40. Cerca con Google

305. Vorhees CV, Brunner RL, McDaniel CR, Butcher RE: The relationship of gestational age to vitamin A induced postnatal dysfunction. Teratology. 1978;17(3):271-5. Cerca con Google

306. Vorhees CV: Teratogenicity and developmental toxicity of valproic acid in rats.Teratology. 1987; 35(2):195-202. Cerca con Google

307. Wagner CL, Katikaneni LD, Cox TH, Ryan RM.: The impact of prenatal drug exposure on the neonate. Obstet Gynecol Clin North Am. 1998;25(1):169-94. Cerca con Google

308. Weinstock M: Alterations induced by gestational stress in brain morphology and behaviour of the offspring. Prog Neurobiol. 2001;65(5):427-51 Cerca con Google

309. Wells PG, Winn LM: Biochemical toxicology of chemi-cal teratogenesis. Crit Rev Biochem Mol Biol. 1996;31 (1):1-40. Cerca con Google

310. Werler MM, Lammer EJ, Rosenberg L, Mitchell AA: Maternal vitamin A supplementation in relation to selected birth defects. Teratology 1990;42:497-503. Cerca con Google

311. Werler, MM, Lammer EJ, Mitchell AA: Teratogenicity of high vitamin A intake. N Engl J Med.1996; 334(18):1195-6. Cerca con Google

312. West CE: Meeting requirements for vitamin A. Nutr Rev 2000; 58 (11): 341-345. Cerca con Google

313. West KP Jr, Katz J, Khatry SK, LeClerq SC, Pradhan EK, Shrestha SR, Connor PB, Dali SM, Christian P, Pokhrel RP, Sommer a: Double blind, cluster randomised trial of low dose supplementation with vitamin A or â-carotene on mortality related to pregnancy in Nepal. BMJ. 1999;318(7183):570-5. Cerca con Google

314. Wiegand W, Chou RC: Pharmacokinetics of oral isotretinoin. J Am Acad Dermatol. 1998;39:8-12. Cerca con Google

315. Wilcox AJ, Weinberg CR, O'Connor JF, Baird DD, Schlatterer JP, Canfield RE, Armstrong EG, Nisula BC: Incidence of early loss of pregnancy. N Engl J Med. 1988;319(4):189-94. Cerca con Google

316. Willhite CC, Balogh-Nair V: Developmental toxicology of retinylidene methyl nitrone in the golden hamster. Toxicology. 1984;33(3-4):331-40. Cerca con Google

317. Willhite CC, Balogh-Nair V: Teratogenic profile of retinylidene methyl nitrone and retinol in Swiss-Webster mice. Teratog Carcinog Mutagen. 1985;5(5):355-63. Cerca con Google

318. Willhite CC, Sharma RP, Allen PV, Berry DL: Percutaneous retinoid absorption and embryotoxicity. J Invest Dermatol 1990;95(5):523- 9. Cerca con Google

319. Williams G, King J, Cunningham M, Stephan M, Kerr B, Hersh JH: Fetal valproate syndrome and autism: additional evidence of an association. Dev Med Child Neurol. 2001;43(3):202-6. Cerca con Google

320. Williams KJ, Ferm VH, Willhite CC: Teratogenic dose-response relationships of etretinate in the golden hamster. Fundam Appl Toxicol. 1984;4(6):977-82. Cerca con Google

321. Wilson JG, Roth CB, Warkany J: An analysis of the syndrome of malformations induced by maternal vitamin A deficiency. Effects of restoration of vitamin A at various times during gestation. Am J Anat. 1953;92(2):189-217. Cerca con Google

322. Wilson JG: Use of primates in teratological research and testing. In: Malformations Congenitales Des Mammiferes. H. Tuchmann-Duplessis (ed.), Paris: Masson, 1971; 277-280. Cerca con Google

323. Wilton LV, Pearce GL, Martin RM, Mackay FJ, Mann RD: The outcomes of pregnancy in women exposed to newly marketed drugs in general practice in England. Br J Obstet Gynaecol. 1998;105(8): 882-9. Cerca con Google

324. Wisner KL, Gelenberg AJ, Leonard H, Zarin D, Frank E. Pharmacologic treatment of depression during pregnancy. JAMA. 1999;282(13):1264-9. Cerca con Google

325. Wisner KL, Zarin DA, Holmboe ES, Appelbaum PS, Gelenberg AJ, Leonard HL, Frank E. Riskbenefit decision making for treatment of depression during pregnancy. Am J Psychiatry. 2000;157(12):1933-40. Cerca con Google

326. Woutersen RA, Wolterbeek AP, Appel MJ, van den Berg H, Goldbohm RA, Feron VJ: Safety evaluation of synthetic beta-carotene. Crit Rev Toxicol. 1999;29(6):515-42. Cerca con Google

327. Yaris F, Kadioglu M, Kesim M, Ulku C, Yaris E, Kalyoncu NI, Unsal M: Newer antidepressants in pregnancy: prospective outcome of a case series. Reprod Toxicol. 2004;19(2):235-8. Cerca con Google

328. Yaris F, Kadioglu M, Kesim M, Ulku C, Yaris E, Kalyoncu NI: Barbexaclone use in pregnancy. Saudi Med J. 2004;25(2):245-6. Cerca con Google

329. Yerby MS. Management issues for women with epilepsy: neural tube defects and folic acid supplementation. Neurology. 2003;61(6 Suppl 2):S23-6. Cerca con Google

330. Yerby MS. Pregnancy, teratogenesis, and epilepsy. Neurol Clin. 1994;12(4):749-71. Cerca con Google

331. Yip JE, Kokich VG, Shepard TH: The effect of high doses of retinoic acid on prenatal craniofacial development in Macaca nemestrina. Teratology. 1980;21(1):29-38. Cerca con Google

332. Yuschak MM, Gautieri RF: Teratogenicity of 13-cis retinoic acid and phenobarbital sodium in CF- 1 mice. Res Commun Chem Pathol Pharmacol 1993;82(3):259-278. Cerca con Google

333. Zeskind PS, Stephens LE. Maternal selective serotonin reuptake inhibitor use during pregnancy and newborn neurobehavior. Pediatrics. 2004;113(2):368-75. Cerca con Google

334. Zuber C, Librizzi RJ, Vogt BL: Outcomes of pregnancies exposed to high dose vitamin A. Teratology 1987;35(2):42A. Cerca con Google

335. Zuckerman B, Amaro H, Bauchner H, Cabral H. Depressive symptoms during pregnancy: relationship to poor health behaviors. Am J Obstet Gynecol. 1989;160(5 Pt 1):1107-11. Cerca con Google

336. Zupanc ML. Antiepileptic drugs and hormonal contraceptives in adolescent women with epilepsy. Neurology. 2006; 66(6 Suppl 3):S37-45. Cerca con Google

Download statistics

Solo per lo Staff dell Archivio: Modifica questo record