Vai ai contenuti. | Spostati sulla navigazione | Spostati sulla ricerca | Vai al menu | Contatti | Accessibilità

| Crea un account

D'Onofrio, Augusto (2014) Clinical and hemodynamic outcomes of trans-apical aortic valve implantation. insights from the i-ta registry. [Tesi di dottorato]

Full text disponibile come:

[img]
Anteprima
Documento PDF
19Mb

Abstract (inglese)

Senile degenerative calcific aortic valve stenosis (AVS) is a progressive disease characterized by a peculiar natural history. When symptoms begin (congestive heart failure and dyspnea, angina, syncope) mortality rate rapidly increase and quality of life dramatically worsen. It has been estimated that the overall survival of patients with severe symptomatic AVS is less than 50% 2 years after the onset of symptoms. The number of patients suffering from AVS worldwide will increase over time as life expectancy progressively extends.
The treatment of choice for severe symptomatic AVS is aortic valve replacement (AVR) that is usually performed under general anesthesia, with median sternotomy and cardiopulmonary bypass. AVR is a well-established procedure, with excellent early and long-term results and valve prostheses have now reached optimal hemodynamic performance and duration. During the last few years, the development of sutureless aortic bioprosthesis has made easier the surgical procedure. In fact, aortic valve replacement with sutureless valves (SU-AVR) needs shorter cardiopulmonary bypass and aortic cross clamp times and can be safely performed through a minimally invasive approach.
However, a recent survey showed that around 30% of patients with severe symptomatic AVS does not undergo AVR for several reasons: they are not referred for surgery by their family physician or by their cardiologist because of age, they are declined surgery for a high preoperative risk profile; they are inoperable for severe ascending aortic calcification (porcelain aorta).
Trans-catheter aortic valve implantation (TAVI) is an alternative therapeutic option in high-risk or inoperable patients. TAVI can be performed through several accesses: trans-femoral (TF-TAVI), trans-apical (TA-TAVI), trans-aortic (TAo-TAVI) and trans-subclavian (TS-TAVI). This thesis will focus on TAVI and in particular on TA-TAVI in terms of, indications, technique and outcomes.
We will show the results of the Italian Registry of Trans-Apical Aortic Valve Implantation (I-TA) that includes the great majority of patients who underwent TA-TAVI in Italy since this procedure became commercially available in 2008. Furthermore we will present the results of a propensity-matched study that compared all the three available surgical options for patients with severe symptomatic aortic valve stenosis: surgical aortic valve replacement (SAVR), SU-AVR and TA-TAVI. From the results of these two studies it clearly appears that TA-TAVI is an excellent therapeutic options in patients with aortic valve stenosis. The two main issues that still need to be solved are the incidence of paravalvular leak, and valve durability. Paravalvular leak has been demonstrated to have a significant impact on long term survival while the assessment of valve durability needs a longer observation of these patients in order to reach time points when structural valve deterioration is more likely to occur

Abstract (italiano)

La stenosi valvolare aortica (AVS) degenerativa senile è una malattia ad evoluzione progressiva caratterizzata da un significativo aumento della mortalità e da un drammatico peggioramento della qualità della vita dal momento in cui compare la sintomatologia specifica: dispnea (scompenso cardiaco congestizio), angina e sincopi. É stato dimostrato che, dalla comparsa dei sintomi, la sopravvivenza a due anni è inferiore al 50%. La diffusione di questa patologia è in aumento in seguito al progressivo incremento dell’aspettativa di vita, specialmente nei paesi più sviluppati. Il trattamento di prima scelta nei pazienti affetti da AVS severa sintomatica è rappresentato dall’intervento chirurgico di sostituzione valvolare. Questa procedura è generalmente eseguita in anestesia generale attraverso una sternotomia longitudinale mediana e con l’utilizzo della circolazione extracorporea. I risultati dell’intervento di sostituzione valvolare aortica sono ormai ben conosciuti, la sopravvivenza a breve e medio termine è eccellente e le protesi utilizzate hanno dimostrato delle ottime performance sia in termini di durata sia dal punto di vista emodinamico. Negli ultimi anni sono state introdotte sul mercato le bioprotesi aortiche sutureless che non richiedono punti di sutura per ancorarsi sull’anulus aortico. L’intervento di sostituzione valvolare aortica con le protesi sutureless (SU-AVR) richiede, infatti, dei tempi di clampaggio aortico e di circolazione extracorporea inferiori rispetto alle protesi tradizionali ed inoltre può essere più agevolmente eseguito attraverso un accesso mini-invasivo.
Ciononostante, una recente analisi ha evidenziato che circa il 30% dei pazienti affetti da stenosi aortica non sono sottoposti all’intervento cardiochirurgico a causa dell’età molto avanzata o delle severe patologie associate da cui sono affetti.
L’impianto valvolare aortico trans-catetere è un’alternativa terapeutica che può essere considerata nei pazienti ritenuti inoperabili con la tecnica tradizionale oppure per coloro che vengono considerati ad altissimo rischio a causa delle severe patologie coesistenti.
La procedura di TAVI può essere eseguita attraverso diversi approcci: trans-femorale (TF-TAVI), trans-apicale (TA-TAVI), trans-aortico (Tao-TAVI) e trans-succlavio (TS-TAVI). L’argomento di questa Tesi sarà la procedura di TAVI e in particolare rivolgeremo la nostra attenzione alla TAVI trans-apicale in termini d’indicazioni, tecniche e risultati.
In questa tesi saranno presentati i risultati del Registro italiano dell’Impianto Valvolare Aortico per via Trans-Apicale (I-TA registry), in cui sono stati arruolati la grande maggioranza dei pazienti sottoposti a TA-TAVI in Italia dal 2008, anno in cui questa tecnica è stata disponibile. Verranno inoltre presentati i risultati di uno studio propensity-matched in cui sono stati confrontati i risultati di tutte le tre tecniche chirurgiche attualmente disponibili per il trattamento dei pazienti con AVS: SAVR, TA-TAVI e SU-AVR. Dai risultati di questi studi appare chiaramente che la TA-TAVI è una valida alternativa terapeutica nei pazienti con AVS. Ci sono tuttavia ancora due aspetti che richiedono particolare attenzione: l’incidenza di leak paravalvolari e la durata di queste nuove bioprotesi. La presenza di un leak paravalvolare si è dimostrata un fattore prognostico negativo in termini di sopravvivenza a distanza mentre un’effettiva valutazione della durata di queste protesi richiede un’osservazione più prolungata in modo tale da arrivare ad intervalli di tempo in cui il verificarsi di una degenerazione strutturale sia più probabile

Statistiche Download - Aggiungi a RefWorks
Tipo di EPrint:Tesi di dottorato
Relatore:Gerosa, Gino - Basso, Cristina
Dottorato (corsi e scuole):Ciclo 26 > Scuole 26 > SCIENZE MEDICHE, CLINICHE E SPERIMENTALI > SCIENZE CARDIOVASCOLARI
Data di deposito della tesi:28 Gennaio 2014
Anno di Pubblicazione:28 Gennaio 2014
Parole chiave (italiano / inglese):trans-catheter aortic valve implantation, aortic stenosis, cardiac surgery
Settori scientifico-disciplinari MIUR:Area 06 - Scienze mediche > MED/23 Chirurgia cardiaca
Struttura di riferimento:Dipartimenti > Dipartimento di Scienze Cardiologiche, Toraciche e Vascolari
Codice ID:6531
Depositato il:12 Nov 2014 13:23
Simple Metadata
Full Metadata
EndNote Format

Bibliografia

I riferimenti della bibliografia possono essere cercati con Cerca la citazione di AIRE, copiando il titolo dell'articolo (o del libro) e la rivista (se presente) nei campi appositi di "Cerca la Citazione di AIRE".
Le url contenute in alcuni riferimenti sono raggiungibili cliccando sul link alla fine della citazione (Vai!) e tramite Google (Ricerca con Google). Il risultato dipende dalla formattazione della citazione.

1. Piazza N, de Jaegere P, Schultz C, Becker AE, Serruys PW, Anderson RH. Anatomy of the Aortic Valvar Complex and Its Implications for Transcatheter Implantation of the Aortic Valve. Circ Cardiovasc Intervent. 2008;1:74-81 Cerca con Google

2. Ross J, Braunwald E. Aortic stenosis. Circulation. 1968;38:61-67 Cerca con Google

3. Kelly TA, Rothbart RM, Cooper CM, Kaiser DL, Smucker ML, Gibson RS. Comparison of outcome of asymptomatic to symptomatic patients older that 20 years of age with valvular aortic stenosis. Am J Cardiol. 1988;61:123-130 Cerca con Google

4. Otto CM, Lind BK, Kitzman DW, Gersh BJ, Siscovick DS. Association of aortic valve sclerosis with cardiovascular mortality and morbidity in the elderly. N Engl J Med. 1999; 341:142-147 Cerca con Google

5. Fedak PW, David TE, Borger M, Verma S, Butany J, Weisel RD. Bicuspid aortic valve disease: recent insights in pathophysiology and treatment. Expert Rev Cardiovasc ther. 2005;3:295-308 Cerca con Google

6. O'Brien KD, Shavelle DM, Caulfield MT, McDonald TO, Olin-Lewis K, Otto CM, Probstfield JL.. Association of angiotensin-converting enzyme with low-density lipoprotein in aortic valvular lesions and in human plasma. Circulation. 2002;106:2224-2230 Cerca con Google

7. Sarphie TG. A cytochemical study of the surface properties of aortic and mitral valve endothelium from hypercholesterolemic rabbits. Exp Mol Pathol. 1986;44:281-296 Cerca con Google

8. O’Brien KD, Reichenbach DD, Marcovina SM, Kuusisto J, Alpers CE, Otto CM. Apolipoprotein B, (a), and E accumulate in the morphologically early lesion of “degenerative” valvular aortic stenosis. Arterioscler Thromb Vasc Biol. 1996;16:523-532 Cerca con Google

9. Bonow RO, Carabello BA, Chatterjee K, de Leon AC Jr, Faxon DP, Freed MD, Gaasch WH, Lytle BW, Nishimura RA, O'Gara PT, O'Rourke RA, Otto CM, Shah PM, Shanewise JS. 2006 Writing Committee Members; American College of Cardiology/American Heart Association Task Force. 2008 focused update incorporated into the ACC/AHA 2006 guidelines for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association task-force on practice guidelines. Circulation. 2008;118:e523-661 Cerca con Google

10. Alpert JS. Aortic stenosis: a new face for an old disease. Arch Int Med. 2003;163:1769-1770 Cerca con Google

11. Dahl JS, Christensen NL, Videbæk L, Poulsen MK, Carter-Storch R, Hey TM, Pellikka PA, Steffensen FH, Møller JE. Left Ventricular Diastolic Function Is Associated with Symptom Status in Severe Aortic Valve Stenosis. Circ Imaging. 2013;10:1161 Cerca con Google

12. Tissot CM, Attias D, Himbert D, Ducrocq G, Iung B, Dilly MP, Juliard JM, Lepage L, Détaint D, Messika-Zeitoun D, Nataf P, Vahanian A. Reappraisal of percutaneous aortic balloon valvuloplasty as a preliminary treatment strategy in the transcatheter aortic valve implantation era. EuroIntervention 2011;7:49–56. Cerca con Google

13. Joint Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology (ESC); European Association for Cardio-Thoracic Surgery (EACTS), Vahanian A, Alfieri O, Andreotti F, Antunes MJ, Barón-Esquivias G, Baumgartner H, Borger MA, Carrel TP, De Bonis M, Evangelista A, Falk V, Iung B, Lancellotti P, Pierard L, Price S, Schäfers HJ, Schuler G, Stepinska J, Swedberg K, Takkenberg J, Von Oppell UO, Windecker S, Zamorano JL, Zembala M. Guidelines on the management of valvular heart disease (version 2012). Eur Heart J. 2012;33:2451–2496 Cerca con Google

14. Vahanian A, Iung B, Pierard L, Dion R, Pepper J. Valvular heart disease. In: Camm AJ, Lu¨scher TF, Serruys PW, ed. The ESC Textbook of Cardiovascular Medicine, 2nd Edition. Malden/Oxford/Victoria: Blackwell Publishing Ltd; 2009:625–670 Cerca con Google

15. The European Association for Cardio-Thoracic Surgery. Fourth EACTS adult cardiac surgical database report 2010. Henley-on-Thames, UK Dendrite Clinical Systems Ltd; ISBN 9781-9039-682-60. Cerca con Google

16. The Society of Thoracic Surgeons. Adult cardiac surgery database, executive summary, 10 years STS report. http://www.sts.org/sites/default/files/documents/pdf/ndb2010/1stHarvestExecutiveSummary%5B1%5D.pdf. Vai! Cerca con Google

17. Bridgewater B, Keogh B, Kinsman R, Walton P. The Society for Cardiothoracic Surgery in Great Britain & Ireland, 6th national adult cardiac surgical database report; demonstrating quality, 2008. Henley-on-Thames, UK: Dendrite Clinical Systems Ltd; ISBN 1-903968-23-2, published July 2009. Cerca con Google

18. Gummert JF, Funkat A, Beckmann A, Schiller W, Hekmat K, Ernst M, Beyersdorf F. Cardiac surgery in Germany during 2009. A report on behalf of the German Society for Thoracic and Cardiovascular Surgery. Thorac Cardiovasc Surg 2010;58:379–386. Cerca con Google

19. Brown JM, O’Brien SM, Wu C, Sikora JAH, Griffith BP, Gammie JS. Isolated aortic valve replacement in North America comprising 108,687 patients in 10 years: changes in risks, valve types, and outcomes in the Society of Thoracic Surgeons National Database. J Thorac Cardiovasc Surg 2009;137:82–90. Cerca con Google

20. El Bardissi AW, Shekar P, Couper GS, Cohn LH. Minimally invasive aortic valve replacement in octogenarian, high-risk, transcatheter aortic valve implantation candidates. J Thorac Cardiovasc Surg 2011;141:328–335. Cerca con Google

21. Chukwuemeka A, Borger MA, Ivanov J, Armstrong S, Feindel C, David T. Valve surgery in octogenarians: a safe option with good medium-term results. J Heart Valve Dis 2006;15:191–196. Cerca con Google

22. Gummert JF, Funkat AK, Beckmann A, Ernst M, Hekmat K, Beyersdorf F, Schiller W. Cardiac surgery in Germany during 2010: a report on behalf of the German Society for Thoracic and Cardiovascular Surgery. Thorac Cardiovasc Surg 2011;59:259–267. Cerca con Google

23. Emery RW, Krogh CC, Arom KV, Emery AM, Benyo-Albrecht K, Joyce LD, Nicoloff DM. The St. Jude Medical cardiac valve prosthesis: a 25-year experience with single valve replacement. Ann Thorac Surg 2005;79:776–782. Cerca con Google

24. Jamieson WR, Burr LH, Miyagishima RT, Germann E, Macnab JS, Stanford E, Chan F, Janusz MT, Ling H. Carpentier-Edwards supra-annular aortic porcine bioprosthesis: clinical performance over 20 years. J Thorac Cardiovasc Surg 2005;130:994–1000. Cerca con Google

25. D'Onofrio A, Auriemma S, Magagna P, Favaro A, Cannarella A, Piccin C, Bilotta M, Abbiate N, Lamascese N, Fabbri A. Aortic valve replacement with the Sorin Pericarbon Freedom stentless prosthesis: 7 years' experience in 130 patients. J Thorac Cardiovasc Surg. 2007;134:491-495. Cerca con Google

26. Brown ML, McKellar SH, Sundt TM, Schaff HV. Ministernotomy versus conventional sternotomy for aortic valve replacement: a systematic review and meta-analysis. J Thorac Cardiovasc Surg 2009;137:670–679. Cerca con Google

27. Cox J, Ad N, Myers K, Gharib M, Quijano RC. Tubular heart valves: A new tissue prosthesis design-Preclinical evaluation of the 3f aortic bioprosthesis. J Thoracic Surg. 2005;130:520-527 Cerca con Google

28. Leyh R, Yildirim C, Buck T, Sommer S, Herold U, Jakob H. Early single-center experience with the 3F-enable aortic valve bioprosthesis. Herz. 2006;31:423-428 Cerca con Google

29. Martens S, Sadowski J, Eckstein FS, Bartus K, Kapelak B, Sievers HH, Schlensak C, Carrel T. Clinical experience with the ATS 3f Enable Sutureless Bioprosthesis. Eur J Cardiothorac Surg. 2011;40:749-755 Cerca con Google

30. Shrestha M, Folliguet T, Meuris B, Dibie A, Bara C, Herregods MC, Khaladj N, Hagl C, Flameng W, Laborde F, Haverich A. Sutureless Perceval S aortic valve replacement: a multicenter, prospective pilot trial. J Heart Valve Dis. 2009;18:698-702 Cerca con Google

31. Flameng W, Herregods MC, Hermans H, Van der Mieren G, Vercalsteren M, Poortmans G, Van Hemelrijck J, Meuris B. Effect of sutureless implantation of the Perceval S aortic valve bioprosthesis on intraoperative and early postoperative outcomes. J Thorac Cardiovasc Surg. 2011;142:1453-1457 Cerca con Google

32. Kocher AA, Laufer G, Haverich A, Shrestha M, Walther T, Misfeld M, Kempfert J, Gillam L, Schmitz C, Wahlers TC, Wippermann J, Mohr FW, Roth M, Skwara A,Rahmanian P, Wiedemann D, Borger MA. One-year outcomes of the Surgical Treatment of Aortic Stenosis With a Next Generation Surgical Aortic Valve (TRITON) trial: a prospective multicenter study of rapid-deployment aortic valve replacement with the EDWARDS INTUITY Valve System. J Thorac Cardiovasc Surg. 2013 ;145:110-115 Cerca con Google

33. Davies H. Catheter-mounted valve for temporary relief of aortic insufficiency. Lancet 1965;285:250. Cerca con Google

34. Binder RK, Webb JG. TAVI: from homemade prosthesis to global interventional phenomenon. Heart 2012;98:iv30–iv36 Cerca con Google

35. Moulopoulos SD, Anthopoulos L, Stamatelopoulos S, Stefadouros M. Catheter-mounted aortic valves. Ann Thorac Surg 1971;11:423–430 Cerca con Google

36. Cribier A, Savin T, Saoudi N, Rocha P, Berland J, Letac B. Percutaneous transluminal valvuloplasty of acquired aortic stenosis in elderly patients: an alternative to valve replacement? Lancet 1986;1:63–67. Cerca con Google

37. Lieberman EB, Bashore TM, Hermiller JB, Wilson JS, Pieper KS, Keeler GP, Pierce CH, Kisslo KB, Harrison JK, Davidson CJ. Balloon aortic valvuloplasty in adults: failure of procedure to improve long-term survival. J Am Coll Cardiol 1995;26:1522–1528. Cerca con Google

38. Andersen HR, Knudsen LL, Hasenkam JM. Transluminal implantation of artificial heart valves. Description of a new expandable aortic valve and initial results with implantation by catheter technique in closed chest pigs. Eur Heart J 1992;13:704–708. Cerca con Google

39. Cribier A, Eltchaninoff H, Bash A, Borenstein N, Tron C, Bauer F, Derumeaux G, Anselme F, Laborde F, Leon MB. Percutaneous transcatheter implantation of an aortic valve prosthesis for calcific aortic stenosis: first human case description. Circulation 2002;106:3006–3008. Cerca con Google

40. Grube E, Laborde JC, Zickmann B, Gerckens U, Felderhoff T, Sauren B, Bootsveld A, Buellesfeld L, Iversen S. First report on a human percutaneous transluminal implantation of a self-expanding valve prosthesis for interventional treatment of aortic valve stenosis. Catheter Cardiovasc Interv 2005;66:465–469. Cerca con Google

41. Lichtenstein SV, Cheung A, Ye J, Thompson CR, Carere RG, Pasupati S, Webb JG. Transapical transcatheter aortic valve implantation in humans: initial clinical experience. Circulation 2006;114:591–596. Cerca con Google

42. Walther T, Falk V, Borger MA, Dewey T, Wimmer-Greinecker G, Schuler G, Mack M, Mohr FW. Minimally invasive transapical beating heart aortic valve implantation—proof of concept. Eur J Cardiothorac Surg 2007;31:9–15. Cerca con Google

43. Ye J, Cheung A, Lichtenstein SV, Carere RG, Thompson CR, Pasupati S, Webb JG. Transapical aortic valve implantation in humans. J Thorac Cardiovasc Surg 2006;131:1194–1196. Cerca con Google

44. Webb JG, Chandavimol M, Thompson CR, Ricci DR, Carere RG, Munt BI, Buller CE, Pasupati S, Lichtenstein S. Percutaneous aortic valve implantation retrograde from the femoral artery. Circulation 2006;113:842–850. Cerca con Google

45. Cribier A, Eltchaninoff H, Tron C, Bauer F, Agatiello C, Nercolini D, Tapiero S, Litzler PY, Bessou JP, Babaliaros V. Treatment of calcific aortic stenosis with the percutaneous heart valve: mid-term follow-up from the initial feasibility studies: the French experience. J Am Coll Cardiol. 2006;47:1214–1223. Cerca con Google

46. Grube E, Laborde JC, Gerckens U, Felderhoff T, Sauren B, Buellesfeld L, Mueller R, Menichelli M, Schmidt T, Zickmann B, Iversen S, Stone GW. Percutaneous implantation of the CoreValve self-expanding valve prosthesis in high-risk patients with aortic valve disease: the Siegburg first-in-man study. Circulation 2006;114:1616–1624 Cerca con Google

47. Leon MB, Smith CR, Mack M, Miller DC, Moses JW, Svensson LG, Tuzcu EM, Webb JG, Fontana GP, Makkar RR, Brown DL, Block PC, Guyton RA, Pichard AD, Bavaria JE, Herrmann HC, Douglas PS, Petersen JL, Akin JJ, Anderson WN, Wang D, Pocock S; PARTNER Trial Investigators. Transcatheter aortic-valve implantation for aortic stenosis in patients who cannot undergo surgery. N Engl J Med 2010;363:1597–1607 Cerca con Google

48. Makkar RR, Fontana GP, Jilaihawi H, Kapadia S, Pichard AD, Douglas PS, Thourani VH, Babaliaros VC, Webb JG, Herrmann HC, Bavaria JE, Kodali S, Brown DL, Bowers B, Dewey TM, Svensson LG, Tuzcu M, Moses JW, Williams MR, Siegel RJ, Akin JJ, Anderson WN, Pocock S, Smith CR, Leon MB; PARTNER Trial Investigators. Transcatheter aortic-valve replacement for inoperable severe aortic stenosis. N Engl J Med 2012;366:1696–1704 Cerca con Google

49. Smith CR, Leon MB, Mack MJ, Miller DC, Moses JW, Svensson LG, Tuzcu EM, Webb JG, Fontana GP, Makkar RR, Williams M, Dewey T, Kapadia S, Babaliaros V, Thourani VH, Corso P, Pichard AD, Bavaria JE, Herrmann HC, Akin JJ, Anderson WN, Wang D, Pocock SJ; PARTNER Trial Investigators. Transcatheter versus surgical aortic-valve replacement in high-risk patients. N Engl J Med 2011;364:2187–2198 Cerca con Google

50. Kempfert J, Walther T, Borger MA, Lehmann S, Blumenstein J, Fassl J, Schuler G, Mohr FW. Minimally invasive off-pump aortic valve implantation: the surgical safety net. Ann Thorac Surg. 2008;86:1665-1668 Cerca con Google

51. Gerosa G, Fabozzo A, Bianco R, Tarantini G, D'Onofrio A. Trans-aortic balloon-expandable aortic valve implantation. J Thorac Cardiovasc Surg. 2012;143:1453-1455 Cerca con Google

52. D'Onofrio A, Rubino P, Fusari M, Salvador L, Musumeci F, Rinaldi M, Vitali EO, Glauber M, Di Bartolomeo R, Alfieri OR, Polesel E, Aiello M, Casabona R, Livi U, Grossi C, Cassese M, Pappalardo A, Gherli T, Stefanelli G, Faggian GG, Gerosa G. Clinical and hemodynamic outcomes of "all-comers" undergoing transapical aortic valve implantation: results from the Italian Registry of Trans-Apical Aortic Valve Implantation (I-TA). J Thorac Cardiovasc Surg. 2011 ;142:768-775 Cerca con Google

53. Rodés-Cabau J, Webb JG, Cheung A, Ye J, Dumont E, Feindel CM, Osten M, Natarajan MK, Velianou JL, Martucci G, DeVarennes B, Chisholm R, Peterson MD, Lichtenstein SV, Nietlispach F, Doyle D, DeLarochellière R, Teoh K, Chu V, Dancea A, Lachapelle K, Cheema A, Latter D, Horlick E. Transcatheter aortic valve implantation for the treatment of severe symptomatic aortic stenosis in patients at very high or prohibitive surgical risk: acute and late outcomes of the multicenter Canadian experience. J Am Coll Cardiol. 2010;55:1080-1090 Cerca con Google

54. Li X, Kong M, Jiang D, Dong A. Comparison 30-day clinical complications between transfemoral versus transapical aortic valve replacement for aortic stenosis: a meta-analysis review. J Cardiothorac Surg. 2013;8:168 Cerca con Google

55. Panchal HB, Ladia V, Desai S, Shah T, Ramu V. A meta-analysis of mortality and major adverse cardiovascular and cerebrovascular events following transcatheter aortic valve implantation versus surgical aortic valve replacement for severe aortic stenosis. Am J Cardiol. 2013;112:850-860 Cerca con Google

56. Sharma A, Arbab-Zadeh A, Dubey D, Shani J, Lazar J, Frankel R. Access site bleeding after transcatheter aortic valve implantation. J Thromb Thrombolysis. 2013;35:463-468 Cerca con Google

57. Fraccaro C, Napodano M, Tarantini G. Conduction disorders in the setting of transcatheter aortic valve implantation: a clinical perspective. Catheter Cardiovasc Interv. 2013;81:1217-1223 Cerca con Google

58. Kahlert P, Al-Rashid F, Plicht B, Hildebrandt H, Patsalis P, Chilali KE, Wendt D, Thielmann M, Bergmann L, Kottenberg E, Schlamann M, Eggebrecht H, Jakob H, Heusch G, Konorza T, Erbel R. Incidence, predictors, origin and prevention of early and late neurological events after transcatheter aortic valve implantation (TAVI): a comprehensive review of current data. J Thromb Thrombolysis. 2013;35:436-449 Cerca con Google

59. Kasel AM, Cassese S, Bleiziffer S, Amaki M, Hahn RT, Kastrati A, Sengupta PP. Standardized Imaging for Aortic Annular Sizing Implications for Transcatheter Valve Selection. J Am Coll Cardiol Img 2013;6:249 – 262 Cerca con Google

60. Di Mario C, Eltchaninoff H, Moat N, Goicolea J, Ussia GP, Kala P, Wenaweser P, Zembala M, Nickenig G, Alegria Barrero E, Snow T, Iung B, Zamorano P,Schuler G, Corti R, Alfieri O, Prendergast B, Ludman P, Windecker S, Sabate M, Gilard M, Witowski A, Danenberg H, Schroeder E, Romeo F, Macaya C, Derumeaux G, Maggioni A, Tavazzi L; Transcatheter Valve Treatment Sentinel Registry (TCVT) Investigators of the EURObservational Research Programme (EORP) of the European Society of Cardiology. The 2011-12 pilot European Sentinel Registry of Transcatheter Aortic Valve Implantation: in-hospital results in 4,571 patients. EuroIntervention. 2013;8:1362-1371 Cerca con Google

61. Kempfert J, Rastan AJ, Beyersdorf F, Schönburg M, Schuler G, Sorg S, Mohr FW, Walther T. Trans-apical aortic valve implantation using a new self-expandable bioprosthesis: initial outcomes. Eur J Cardiothorac Surg 2011;40:1114–1119 Cerca con Google

62. Holzhey D, Linke A, Treede H, Baldus S, Bleiziffer S, Wagner A, Börgermann J, Scholtz W, Vanoverschelde JL, Falk V. Intermediate follow-up results from the multicenter engager European pivotal trial. Ann Thorac Surg. 2013;96:2095-2100 Cerca con Google

63. Meredith Am IT, Worthley SG, Whitbourn RJ, Antonis P, Montarello JK, Newcomb AE, Lockwood S, Haratani N, Allocco DJ, Dawkins KD. Transfemoral aortic valve replacement with the repositionable Lotus Valve System in high surgical risk patients: the REPRISE I study. EuroIntervention. 2013 Oct 31. pii: 20131009-02 Cerca con Google

64. The PARTNER II Trial: Placement of AoRTic TraNscathetER Valves. http://clinicaltrials.gov/ct2/show/NCT01314313 Vai! Cerca con Google

65. D'Onofrio A, Fusari M, Abbiate N, Zanchettin C, Bianco R, Fabbri A, Salvador L, Polesel E, Biglioli P, Gerosa G. Transapical aortic valve implantation in high-risk patients with severe aortic valve stenosis. Ann Thorac Surg. 2011;92:1671-1677 Cerca con Google

66. Généreux P, Head SJ, Hahn R, Daneault B, Kodali S, Williams MR, van Mieghem NM, Alu MC, Serruys PW, Kappetein AP, Leon MB. Paravalvular leak after transcatheter aortic valve replacement: the new Achilles' heel? A comprehensive review of the literature. J Am Coll Cardiol. 2013;61:1125-36 Cerca con Google

67. Lerakis S, Hayek SS, Douglas PS. Paravalvular aortic leak after transcatheter aortic valve replacement: current knowledge. Circulation. 2013;127:397-407 Cerca con Google

68. Von Segesser LK, Gerosa G, Borger MA, Ferrari E. Prevention and management of potential adverse events during transapical aortic valve replacement. J Heart Valve Dis. 2013;22:276-286 Cerca con Google

69. Kodali SK, Williams MR, Smith CR, Svensson LG, Webb JG, Makkar RR, Fontana GP, Dewey TM, Thourani VH, Pichard AD, Fischbein M, Szeto WY, Lim S,Greason KL, Teirstein PS, Malaisrie SC, Douglas PS, Hahn RT, Whisenant B, Zajarias A, Wang D, Akin JJ, Anderson WN, Leon MB; PARTNER Trial Investigators. Two-year outcomes after transcatheter or surgical aortic-valve replacement. N Engl J Med. 2012;366:1686-1695 Cerca con Google

70. Gilard M, Eltchaninoff H, Iung B, Donzeau-Gouge P, Chevreul K, Fajadet J, Leprince P, Leguerrier A, Lievre M, Prat A, Teiger E, Lefevre T, Himbert D, Tchetche D, Carrié D, Albat B, Cribier A, Rioufol G, Sudre A, Blanchard D, Collet F, Dos Santos P, Meneveau N, Tirouvanziam A, Caussin C, Guyon P, Boschat J, Le Breton H, Collart F, Houel R, Delpine S, Souteyrand G, Favereau X, Ohlmann P, Doisy V, Grollier G, Gommeaux A, Claudel JP, Bourlon F, Bertrand B, Van Belle E, Laskar M; FRANCE 2 Investigators. Registry of transcatheter aortic-valve implantation in high-risk patients. N Engl J Med. 2012;366:1705-1715 Cerca con Google

71. Zahn R, Gerckens U, Linke A, Sievert H, Kahlert P, Hambrecht R, Sack S, Abdel-Wahab M, Hoffmann E, Schiele R, Schneider S, Senges J. German Transcatheter Aortic Valve Interventions-Registry Investigators. Predictors of one-year mortality after transcatheter aortic valve implantation for severe symptomatic aortic stenosis. Am J Cardiol. 2013;112:272-9 Cerca con Google

72. Hamm CW, Möllmann H, Holzhey D, Beckmann A, Veit C, Figulla HR, Cremer J, Kuck KH, Lange R, Zahn R, Sack S, Schuler G, Walther T, Beyersdorf F, Böhm M, Heusch G, Funkat AK, Meinertz T, Neumann T, Papoutsis K, Schneider S, Welz A, Mohr FW; for the GARY-Executive Board. The German Aortic Valve Registry (GARY): in-hospital outcome. Eur Heart J. 2013 doi: 10.1093/eurheartj/eht381 Cerca con Google

73. Beckmann A, Hamm C, Figulla HR, Cremer J, Kuck KH, Lange R, Zahn R, Sack S, Schuler GC, Walther T, Beyersdorf F, Böhm M, Heusch G, Funkat AK, Meinertz T, Neumann T, Papoutsis K, Schneider S, Welz A, Mohr FW; GARY Executive Board. The German Aortic Valve Registry (GARY): a nationwide registry for patients undergoing invasive therapy for severe aortic valve stenosis. Thorac Cardiovasc Surg. 2012;60:319-325 Cerca con Google

74. Della Barbera M, Valente M, Basso C, Thiene G. Pericardial traumatic injury in trans-catheter aortic valve implantation. Eur J Cardiothorac Surg. 2013;43:493-494 Cerca con Google

75. Amahzoune B, Bruneval P, Allam B, Lafont A, Fabiani JN, Zegdi R. Traumatic leaflet injury during the use of percutaneous valves: a comparative study of balloon- and self-expandable valved stents. Eur J Cardiothorac Surg. 2013;43:488-493 Cerca con Google

76. Hayashida K, Romano M, Lefèvre T, Chevalier B, Farge A, Hovasse T, Le Houerou D, Morice MC. The trans-aortic approach for transcatheter aortic valve implantation: a valid alternative to the transapical access in patients with no peripheral vascular option. A single center experience. Eur J Cardiothorac Surg. 2013;44:692-700 Cerca con Google

77. Bapat V, Khawaja MZ, Attia R, Narayana A, Wilson K, Macgillivray K, Young C, Hancock J, Redwood S, Thomas M. Trans-aortic Transcatheter Aortic valve implantation using Edwards Sapien valve: a novel approach. Catheter Cardiovasc Interv. 2012;79:733-740 Cerca con Google

78. Rajani R, Hancock J, Chambers JB. The art of assessing aortic stenosis. Heart 2012;98:14-22 Cerca con Google

79. Bauer T, Linke A, Sievert H, Kahlert P, Hambrecht R, Nickenig G, Hauptmann KE, Sack S, Gerckens U, Schneider S, Zeymer U, Zahn R. Comparison of the Effectiveness of Transcatheter Aortic Valve Implantation in Patients With Stenotic Bicuspid Versus Tricuspid Aortic Valves (from the German TAVI Registry). Am J Cardiol. 2013. doi: 10.1016/j.amjcard.2013.10.023 Cerca con Google

80. Abdel-Wahab M, Zahn R, Horack M, Gerckens U, Schuler G, Sievert H, Eggebrecht H, Senges J, Richardt G. German transcatheter aortic valve interventions registry investigators. Aortic regurgitation after transcatheter aortic valve implantation: incidence and early outcome. Results from the German transcatheter aortic valve interventions registry. Heart. 2011;97:899-906 Cerca con Google

81. Hayashida K, Bouvier E, Lefèvre T, Hovasse T, Morice MC, Chevalier B, Romano M, Garot P, Farge A, Donzeau-Gouge P, Cormier B. Potential mechanism of annulus rupture during transcatheter aortic valve implantation. Catheter Cardiovasc Interv. 2013;82:742-746 Cerca con Google

82. Husser O, Rauch S, Endemann DH, Resch M, Nunez J, Bodi V, Hilker M, Schmid C, Riegger GA, Luchner A, Hengstenberg C. Impact of three-dimensional trans-esophageal echocardiography on prosthesis sizing for transcatheter aortic valve implantation. Catheter Cardiovasc Interv. 2012;80:956-963 Cerca con Google

83. Messika-Zeitoun D, Serfaty JM, Brochet E, Ducrocq G, Lepage L, Detaint D, Hyafil F, Himbert D, Pasi N, Laissy JP, Iung B, Vahanian A. Multimodal assessment of the aortic annulus diameter: implications for transcatheter aortic valve implantation. J Am Coll Cardiol. 2010;55:186-194 Cerca con Google

84. Achenbach S, Delgado V, Hausleiter J, Schoenhagen P, Min JK, Leipsic JA. SCCT expert consensus document on computed tomography imaging before transcatheter aortic valve implantation (TAVI)/transcatheter aortic valve replacement (TAVR). J Cardiovasc Comput Tomogr. 2012:366-380 Cerca con Google

85. Jabbour A, Ismail TF, Moat N, Gulati A, Roussin I, Alpendurada F, Park B, Okoroafor F, Asgar A, Barker S, Davies S, Prasad SK, Rubens M, Mohiaddin RH. Multimodality imaging in transcatheter aortic valve implantation and post-procedural aortic regurgitation: comparison among cardiovascular magnetic resonance, cardiac computed tomography, and echocardiography. J Am Coll Cardiol. 2011;58:2165–2173. Cerca con Google

86. Willson AB, Webb JG, LaBounty TM, Achenbach S, Moss R, Wheeler M, Thompson C, Min JK, Gurvitch R, Norgard BL, Hague C, Toggweiler S, Binder RK, Freeman M, Poulson S, Wood DA, Leipsic J. 3-dimensional aortic annular assessment by multidetector computed tomography predicts moderate or severe paravalvular regurgitation after transcatheter aortic valve replacement: implications for sizing of transcatheter heart valves. J Am Coll Cardiol.2012;59:1287–1294. Cerca con Google

87. Altiok E, Koos R, Schroder J, Brehmer K, Hamada S, Becker M, Mahnken AH, Almalla M, Dohmen G, Autschbach R, Marx N, Hoffmann R. Comparison of two-dimensional and three-dimensional imaging techniques for measurement of aortic annulus diameters before transcatheter aortic valve implantation. Heart. 2011;97:1578–1584. Cerca con Google

88. Ng AC, Delgado V, van der Kley F, Shanks M, van de Veire NR, Bertini M, Nucifora G, van Bommel RJ, Tops LF, de Weger A, Tavilla G, de Roos A, Kroft LJ, Leung DY, Schuijf J, Schalij MJ, Bax JJ. Comparison of aortic root dimensions and geometries before and after transcatheter aortic valve implantation by 2- and 3-dimensional trans-esophageal echocardiography and multislice computed tomography. Circ Cardiovasc Imaging. 2010;3:94–102. Cerca con Google

89. Gurvitch R, Webb JG, Yuan R, Johnson M, Hague C, Willson AB, Toggweiler S, Wood DA, Ye J, Moss R, Thompson CR, Achenbach S, Min JK, Labounty TM, Cury R, Leipsic J. Aortic annulus diameter determination by multidetector computed tomography: reproducibility, applicability, and implications for transcatheter aortic valve implantation. JACC Cardiovasc Interv. 2011;4:1235–1245. Cerca con Google

90. Jilaihawi H, Kashif M, Fontana G, Furugen A, Shiota T, Friede G, Makhija R, Doctor N, Leon MB, Makkar RR. Cross-sectional computed tomographic assessment improves accuracy of aortic annular sizing for transcatheter aortic valve replacement and reduces the incidence of paravalvular aortic regurgitation. J Am Coll Cardiol. 2012; 59:1275–1286. Cerca con Google

91. Colli A, Gallo M, Bernabeu E, D'Onofrio A, Tarzia V, Gerosa G. Aortic valve calcium scoring is a predictor of paravalvular aortic regurgitation after transcatheter aortic valve implantation. Ann Cardiothorac Surg. 2012;1:156-159 Cerca con Google

92. Reynolds MR, Magnuson EA, Lei Y, Leon MB, Smith CR, Svensson LG, Webb JG, Babaliaros VC, Bowers BS, Fearon WF, Herrmann HC, Kapadia S, Kodali SK, Makkar RR, Pichard AD, Cohen DJ. Placement of Aortic Transcatheter Valves (PARTNER) Investigators. Placement of aortic transcatheter valves (PARTNER) investigators: health-related quality of life after transcatheter aortic valve replacement in inoperable patients with severe aortic stenosis. Circulation. 2011;124:1964-1972. Cerca con Google

93. Reynolds MR, Magnuson EA, Wang K, Lei Y, Vilain K, Walczak J, Kodali SK, Lasala JM, O'Neill WW, Davidson CJ, Smith CR, Leon MB, Cohen DJ. PARTNER Investigators. Cost effectiveness of transcatheter aortic valve replacement compared with standard care among inoperable patients with severe aortic stenosis: results from the placement of aortic transcatheter valves (PARTNER) trial (cohort B): PARTNER investigators. Circulation. 2012;125:1102-1109. Cerca con Google

94. Miller DC, Blackstone EH, Mack MJ, Svensson LG, Kodali SK, Kapadia S, Rajeswaran J, Anderson WN, Moses JW, Tuzcu EM, Webb JG, Leon MB, Smith CR; PARTNER Trial Investigators and Patients; PARTNER Stroke Substudy Writing Group and Executive Committee. Transcatheter (TAVR) vs surgical (AVR) aortic valve replacement: occurrence, hazard, risk factors, and consequences of neurologic events in the PARTNER trial: the PARTNER trial investigators and patients: the PARTNER Stroke Substudy Writing Group and Executive Committee. J Thorac Cardiovasc Surg. 2012;143:832-843.e13. Cerca con Google

95. Leon MB, Piazza N, Nikolsky E, Blackstone EH, Cutlip DE, Kappetein AP, Krucoff MW, Mack M, Mehran R, Miller C, Morel MA, Petersen J, Popma JJ, Takkenberg JJ, Vahanian A, van Es GA, Vranckx P, Webb JG, Windecker S, Serruys PW. Standardized endpoint definitions for Trans-catheter Aortic Valve Implantation clinical trials: a consensus report from the Valve Academic Research Consortium. J Am Coll Cardiol. 2011;57:253-269 Cerca con Google

96. Kappetein AP, Head SJ, Généreux P, Piazza N, van Mieghem NM, Blackstone EH, Brott TG, Cohen DJ, Cutlip DE, van Es GA, Hahn RT, Kirtane AJ, Krucoff MW, Kodali S, Mack MJ, Mehran R, Rodés-Cabau J, Vranckx P, Webb JG, Windecker S, Serruys PW, Leon MB; Valve Academic Research Consortium 2. Updated standardized endpoint definitions for trans-catheter aortic valve implantation: the Valve Academic Research Consortium-2 consensus document. J Thorac Cardiovasc Surg. 2013;145:6-23 Cerca con Google

97. D'Onofrio A, Salizzoni S, Agrifoglio M, Cota L, Luzi G, Tartara PM, Cresce GD, Aiello M, Savini C, Cassese M, Cerillo A, Punta G, Cioni M, Gabbieri D, Zanchettin C, Agostinelli A, Mazzaro E, Di Gregorio O, Gatti G, Faggian G, Filippini C, Rinaldi M, Gerosa G. Medium term outcomes of transapical aortic valve implantation: results from the Italian Registry of Trans-Apical Aortic Valve Implantation. Ann Thorac Surg. 2013;96:830-835 Cerca con Google

98. D'Onofrio A, Rizzoli G, Messina A, Alfieri O, Lorusso R, Salizzoni S, Glauber M, Di Bartolomeo R, Besola L, Rinaldi M, Troise G, Gerosa G. Conventional surgery, sutureless valves, and transapical aortic valve replacement: what is the best option for patients with aortic valve stenosis? A multicenter, propensity-matched analysis. J Thorac Cardiovasc Surg. 2013;146:1065-1070 Cerca con Google

99. Nashef SA, Roques F, Michel P, Gauducheau E, Lemeshow S, Salamon R. European system for cardiac operative risk evaluation (Euroscore). Eur J Cardiothorac Surg 1999;16:9-13 Thomas M, Schymik G, Walther T, et al. One-year outcomes of cohort 1 in the Edwards SAPIEN Aortic Bioprosthesis European Outcome (SOURCE) registry: the European registry of transcatheter aortic valve implantation using the Edwards SAPIEN valve. Circulation 2011:124:425-33 Cerca con Google

100. Seiffert M, Schnabel R, Conradi L, Diemert P, Schirmer J, Koschyk D, Linder M, Kersten JF, Grosser A, Wilde S, Blankenberg S, Reichenspurner H, Baldus S, Treede H. Predictors and outcomes after transcatheter aortic valve implantation using different approaches according to the valve academic research consortium definitions. Catheter Cardiovasc Interv. 2013;82:640-52 Cerca con Google

101. Blackstone EH. The Right Thing To Do With the Wrong Thing. Ann Thorac Surg 2012;93:1026-6 Cerca con Google

102. Toggweiler S, Humphries KH, Lee M, Binder RK, Moss RR, Freeman M, Ye J, Cheung A, Wood DA, Webb JG. 5-year outcome after transcatheter aortic valve implantation. J Am Coll Cardiol. 2013; 61:413-419 Cerca con Google

103. Austin PC. Propensity-score matching in the cardiovascular surgery literature from 2004 to 2006: a systematic review and suggestions for improvement. J Thorac Cardiovasc Surg. 2007;134:1128-1135. Cerca con Google

104. Becker SO, Ichino A. Estimation of average treatment effects based on propensity scores. Stata J. 2002;2:358-377. Cerca con Google

105. Leuven E, Sianesi B. PSMATCH2: Stata module to perform full Mahalanobis and propensity score matching, common support graphing, and covariate imbalance testing, version 4.0.5. 2003. Available at: http://ideas.repec.org/c/boc/bocode/s432001.html. Vai! Cerca con Google

106. Guo S, Fraser MW. Propensity score analysis: statistical methods and applications. Psychometrika. 2010;75:775-777. Cerca con Google

107. D'Onofrio A, Messina A, Lorusso R, Alfieri OR, Fusari M, Rubino P, Rinaldi M, Di Bartolomeo R, Glauber M, Troise G, Gerosa G. Sutureless aortic valve replacement as an alternative treatment for patients belonging to the "gray zone" between transcatheter aortic valve implantation and conventional surgery: a propensity-matched, multicenter analysis. J Thorac Cardiovasc Surg. 2012;144:1010-1016 Cerca con Google

108. Ledwoch J, Franke J, Gerckens U, Kuck KH, Linke A, Nickenig G, Krülls-Münch J, Vöhringer M, Hambrecht R, Erbel R, Richardt G, Horack M, Zahn R, Senges J, Sievert H. German Transcatheter Aortic Valve Interventions Registry Investigators. Incidence and predictors of permanent pacemaker implantation following transcatheter aortic valve implantation: analysis from the German transcatheter aortic valve interventions registry. Catheter Cardiovasc Interv. 2013;82:569-577 Cerca con Google

Download statistics

Solo per lo Staff dell Archivio: Modifica questo record